Current molecular biology laboratories rely heavily on the purification and manipulation of
nucleic acids. Yet, commonly used centrifuge- and column-based protocols require …

Interferon-inducible transmembrane proteins (IFITMs) are a family of transmembrane proteins.
The subgroup of immunity-related (IR-)IFITMs is involved in adaptive and innate immune …

Guanylate binding proteins (GBPs) represent an evolutionary ancient protein family widely
distributed among eukaryotes. They are interferon (IFN)-inducible guanosine triphosphatases …

Guanylate binding proteins (GBPs) are an evolutionarily ancient family of proteins that are
widely distributed among eukaryotes. They belong to the dynamin superfamily of GTPases, …

The β‐hydroxyacid dehydrogenase from Thermocrinus albus (Ta‐βHAD), which catalyzes
the NADP + ‐dependent oxidation of β‐hydroxyacids, was engineered to accept imines as …

Chiral amines are essential building blocks in biologically active compounds, fine chemicals,
agrochemicals and pharmaceuticals. In the last ten years, various enzymes were identified …

Human immunodeficiency virus (HIV) is the causative agent of acquired immunodeficiency
syndrome (AIDS). Novel strategies to combat this pandemic include the discovery of cellular …

Background The DExD/H domain containing RNA helicases such as retinoic acid-inducible
gene I (RIG-I) and melanoma differentiation-associated gene 5 (MDA5) are key cytosolic …

… ;28 even Schelle claims that Marenzio entered the chapel in 1594, while Celani, in his more
detailed account, implies that Marenzio entered it in 1594 or 1595.29 Schelle's mistake is …

… Given the potential role of LucA in cholesterol metabolism, we constructed lucA mutant in
Mtb Erdman by allelic exchange (Mtb DlucA::hyg) (Figure 1—figure supplement 2A). We first …