User profiles for Lucas AC Souza

Lucas Anjos Souza

- Verified email at ifgoiano.edu.br - Cited by 1095

Lucas AC Souza

- Verified email at cumc.columbia.edu - Cited by 364

[HTML][HTML] Small RNA modifications in Alzheimer's disease

X Zhang, F Trebak, LAC Souza, J Shi, T Zhou… - Neurobiology of …, 2020 - Elsevier
Background While significant advances have been made in uncovering the aetiology of
Alzheimer's disease and related dementias at the genetic level, molecular events at the …

[HTML][HTML] Assessment of muscular strength with the modified sphygmomanometer test: what is the best method and source of outcome values?

LAC Souza, JC Martins, JB Moura… - Brazilian journal of …, 2014 - SciELO Brasil
SciELO - Brasil - Assessment of muscular strength with the modified sphygmomanometer test:
what is the best method and source of outcome values? Assessment of muscular strength …

Alamandine enhances cardiomyocyte contractility in hypertensive rats through a nitric oxide-dependent activation of CaMKII

…, ELX Coelho, MM Silva, LAC Souza… - … of Physiology-Cell …, 2020 - journals.physiology.org
Overstimulation of the renin-angiotensin system (RAS) has been implicated in the pathogenesis
of various cardiovascular diseases. Alamandine is a peptide newly identified as a …

(Pro)renin receptor knockdown in the paraventricular nucleus of the hypothalamus attenuates hypertension development and AT1 receptor-mediated calcium events

LAC Souza, CJ Worker, W Li… - American Journal …, 2019 - journals.physiology.org
Activation of the brain renin-angiotensin system (RAS) is a pivotal step in the pathogenesis
of hypertension. The paraventricular nucleus (PVN) of the hypothalamus is a critical part of …

[HTML][HTML] Avaliação da força muscular pelo teste do esfigmomanômetro modificado: uma revisão da literatura

LAC Souza, JC Martins, LF Teixeira-Salmela… - Fisioterapia em …, 2013 - SciELO Brasil
INTRODUÇÃO: O Teste do esfigmomanômetro modificado (TEM) tem potencial de ampla
aplicação clínica para mensuração da força muscular. OBJETIVO: Realizar uma ampla …

The neuronal (pro) renin receptor and astrocyte inflammation in the central regulation of blood pressure and blood glucose in mice fed a high-fat diet

CJ Worker, W Li, C Feng, LAC Souza… - American Journal …, 2020 - journals.physiology.org
We report here that the neuronal (pro)renin receptor (PRR), a key component of the brain
renin-angiotensin system (RAS), plays a critical role in the central regulation of high-fat-diet (…

[HTML][HTML] Increased (Pro) renin receptor expression in the hypertensive human brain

M Mohsin, LAC Souza, S Aliabadi, CJ Worker… - Frontiers in …, 2020 - frontiersin.org
Overactivation of the renin-angiotensin system (RAS) – a central physiological pathway
involved in controlling blood pressure (BP) – leads to hypertension. It is now well-recognized …

[HTML][HTML] (Pro) Renin Receptor Antagonism Attenuates High-Fat-Diet–Induced Hepatic Steatosis

AJB Gayban, LAC Souza, SG Cooper, E Regalado… - Biomolecules, 2023 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) comprises a spectrum of liver damage directly
related to diabetes, obesity, and metabolic syndrome. The (pro)renin receptor (PRR) has …

(Pro) renin receptor signaling in hypothalamic tyrosine hydroxylase neurons is required for obesity-associated glucose metabolic impairment

S Pan, LAC Souza, CJ Worker, MER Mendez… - JCI …, 2024 - Am Soc Clin Investig
Glucose homeostasis is achieved via complex interactions between the endocrine pancreas
and other peripheral tissues and glucoregulatory neurocircuits in the brain that remain …

Elevated cerebrospinal fluid sodium in hypertensive human subjects with a family history of Alzheimer's disease

LAC Souza, F Trebak, V Kumar… - Physiological …, 2020 - journals.physiology.org
High salt (sodium) intake leads to the development of hypertension despite the fact that
plasma sodium concentration ([Na + ]) is usually normal in hypertensive human patients. …