The selenoprotein glutathione peroxidase 4 (GPX4) prevents ferroptosis by converting lipid
peroxides into nontoxic lipid alcohols. GPX4 has emerged as a promising therapeutic target …

A new member of the Orthomyxoviridae family, influenza D virus (IDV), was first reported in
swine in the Midwest region of the United States. This study aims to extend our knowledge on …

Cattle have been proposed as the natural reservoir of a novel member of the virus family
Orthomyxoviridae , which has been tentatively classified as influenza D virus (IDV). Although …

INTRODUCTION Systematically profiling the effects of genetic perturbations is a powerful
approach that has revealed the molecular basis for a wide range of biological phenomena. …

Influenza D virus (IDV), a new member of the influenza virus family, was first reported in
2011 in swine in Oklahoma, USA, and then soon found in cattle across North America and …

Selfish, non-long terminal repeat (non-LTR) retroelements and mobile group II introns
encode reverse transcriptases (RTs) that can initiate DNA synthesis without substantial base …

Ribosome profiling has unveiled diverse regulation and perturbations of translation through
a transcriptome-wide survey of ribosome occupancy, read out by sequencing of ribosome-…

Influenza D virus (IDV) has been identified in domestic cattle, swine, camelid, and small
ruminant populations across North America, Europe, Asia, South America, and Africa. Our study …

Translation initiation at alternative start sites can dynamically control the synthesis of two or
more functionally distinct protein isoforms from a single mRNA. Alternate isoforms of the …

Activation of T cells requires a rapid surge in cellular protein synthesis. However, the role of
translation initiation in the early induction of specific genes remains unclear. Here, we show …