User profiles for Lucas J. D’Souza
Lucas D'SouzaResearch Professional, University of Arizona Verified email at email.arizona.edu Cited by 288 |
[HTML][HTML] Genetic evidence that uptake of the fluorescent analog 2NBDG occurs independently of known glucose transporters
LJ D'Souza, SH Wright, D Bhattacharya - PLoS One, 2022 - journals.plos.org
The fluorescent derivative of glucose, 2-Deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)-amino]-D-glucose
(2NBDG), is a widely used surrogate reagent to visualize glucose uptake in live …
(2NBDG), is a widely used surrogate reagent to visualize glucose uptake in live …
[HTML][HTML] A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma
Low-passage, serum-free cell lines cultured from patient tumour tissue are the gold-standard
for preclinical studies and cellular investigations of glioblastoma (GBM) biology, yet …
for preclinical studies and cellular investigations of glioblastoma (GBM) biology, yet …
[HTML][HTML] Clinical characteristics and outcomes of patients hospitalized with COVID-19 in Brazil: Results from the Brazilian COVID-19 registry
…, LEA Santos, MA de Souza Cabral, MD Souza… - International Journal of …, 2021 - Elsevier
Objectives To describe the clinical characteristics, laboratory results, imaging findings, and
in-hospital outcomes of COVID-19 patients admitted to Brazilian hospitals. Methods A cohort …
in-hospital outcomes of COVID-19 patients admitted to Brazilian hospitals. Methods A cohort …
[HTML][HTML] I Brazilian registry of heart failure-clinical aspects, care quality and hospitalization outcomes
Background: Heart failure (HF) is one of the leading causes of hospitalization in adults in
Brazil. However, most of the available data is limited to unicenter registries. The BREATHE …
Brazil. However, most of the available data is limited to unicenter registries. The BREATHE …
[HTML][HTML] ABC2-SPH risk score for in-hospital mortality in COVID-19 patients: development, external validation and comparison with other available scores
…, BL Farace, LS Monteiro, MVR Souza-Silva… - International Journal of …, 2021 - Elsevier
Objectives The majority of available scores to assess mortality risk of coronavirus disease
2019 (COVID-19) patients in the emergency department have high risk of bias. Therefore, this …
2019 (COVID-19) patients in the emergency department have high risk of bias. Therefore, this …
[PDF][PDF] Affinity-restricted memory B cells dominate recall responses to heterologous flaviviruses
Memory B cells (MBCs) can respond to heterologous antigens either by molding new
specificities through secondary germinal centers (GCs) or by selecting preexisting clones without …
specificities through secondary germinal centers (GCs) or by selecting preexisting clones without …
[PDF][PDF] Metabolic and transcriptional modules independently diversify plasma cell lifespan and function
Plasma cell survival and the consequent duration of immunity vary widely with infection or
vaccination. Using fluorescent glucose analog uptake, we defined multiple developmentally …
vaccination. Using fluorescent glucose analog uptake, we defined multiple developmentally …
Genomics Research with Undiagnosed Children: Ethical Challenges at the Boundaries of Research and Clinical Care
…, P D'Souza, H Dai, S Dasari, J Davis… - The Journal of …, 2023 - Elsevier
Objective To explore the perspectives of parents of undiagnosed children enrolled in
genomic diagnosis research regarding their motivations for enrolling their children, their …
genomic diagnosis research regarding their motivations for enrolling their children, their …
Hybrids of a genetically engineered antibody and a carbon nanotube transistor for detection of prostate cancer biomarkers
MB Lerner, J D'Souza, T Pazina, J Dailey… - Acs Nano, 2012 - ACS Publications
We developed a novel detection method for osteopontin (OPN), a new biomarker for prostate
cancer, by attaching a genetically engineered single-chain variable fragment (scFv) protein …
cancer, by attaching a genetically engineered single-chain variable fragment (scFv) protein …
[HTML][HTML] Hypothyroidism does not lead to worse prognosis in COVID-19: findings from the Brazilian COVID-19 registry
…, MA de Souza Cabral, MA Floriani, MD Souza… - International Journal of …, 2022 - Elsevier
Background It is not clear whether previous thyroid diseases influence the course and
outcomes of COVID-19. Methods The study is a part of a multicentric cohort of patients with …
outcomes of COVID-19. Methods The study is a part of a multicentric cohort of patients with …