User profiles for Lucas J. D’Souza

Lucas D'Souza

Research Professional, University of Arizona
Verified email at email.arizona.edu
Cited by 288

[HTML][HTML] Genetic evidence that uptake of the fluorescent analog 2NBDG occurs independently of known glucose transporters

LJ D'Souza, SH Wright, D Bhattacharya - PLoS One, 2022 - journals.plos.org
The fluorescent derivative of glucose, 2-Deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)-amino]-D-glucose
(2NBDG), is a widely used surrogate reagent to visualize glucose uptake in live …

[HTML][HTML] A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma

BW Stringer, BW Day, RCJ D'Souza, PR Jamieson… - Scientific reports, 2019 - nature.com
Low-passage, serum-free cell lines cultured from patient tumour tissue are the gold-standard
for preclinical studies and cellular investigations of glioblastoma (GBM) biology, yet …

[HTML][HTML] Clinical characteristics and outcomes of patients hospitalized with COVID-19 in Brazil: Results from the Brazilian COVID-19 registry

…, LEA Santos, MA de Souza Cabral, MD Souza… - International Journal of …, 2021 - Elsevier
Objectives To describe the clinical characteristics, laboratory results, imaging findings, and
in-hospital outcomes of COVID-19 patients admitted to Brazilian hospitals. Methods A cohort …

[HTML][HTML] I Brazilian registry of heart failure-clinical aspects, care quality and hospitalization outcomes

DC Albuquerque, JD Souza Neto, F Bacal… - Arquivos brasileiros de …, 2015 - SciELO Brasil
Background: Heart failure (HF) is one of the leading causes of hospitalization in adults in
Brazil. However, most of the available data is limited to unicenter registries. The BREATHE …

[HTML][HTML] ABC2-SPH risk score for in-hospital mortality in COVID-19 patients: development, external validation and comparison with other available scores

…, BL Farace, LS Monteiro, MVR Souza-Silva… - International Journal of …, 2021 - Elsevier
Objectives The majority of available scores to assess mortality risk of coronavirus disease
2019 (COVID-19) patients in the emergency department have high risk of bias. Therefore, this …

[PDF][PDF] Affinity-restricted memory B cells dominate recall responses to heterologous flaviviruses

…, JL Uhrlaub, D Reinartz, H Zhao, JM Errico, L D'Souza… - Immunity, 2020 - cell.com
Memory B cells (MBCs) can respond to heterologous antigens either by molding new
specificities through secondary germinal centers (GCs) or by selecting preexisting clones without …

[PDF][PDF] Metabolic and transcriptional modules independently diversify plasma cell lifespan and function

WY Lam, A Jash, CH Yao, L D'Souza, R Wong… - Cell reports, 2018 - cell.com
Plasma cell survival and the consequent duration of immunity vary widely with infection or
vaccination. Using fluorescent glucose analog uptake, we defined multiple developmentally …

Genomics Research with Undiagnosed Children: Ethical Challenges at the Boundaries of Research and Clinical Care

…, P D'Souza, H Dai, S Dasari, J Davis… - The Journal of …, 2023 - Elsevier
Objective To explore the perspectives of parents of undiagnosed children enrolled in
genomic diagnosis research regarding their motivations for enrolling their children, their …

Hybrids of a genetically engineered antibody and a carbon nanotube transistor for detection of prostate cancer biomarkers

MB Lerner, J D'Souza, T Pazina, J Dailey… - Acs Nano, 2012 - ACS Publications
We developed a novel detection method for osteopontin (OPN), a new biomarker for prostate
cancer, by attaching a genetically engineered single-chain variable fragment (scFv) protein …

[HTML][HTML] Hypothyroidism does not lead to worse prognosis in COVID-19: findings from the Brazilian COVID-19 registry

…, MA de Souza Cabral, MA Floriani, MD Souza… - International Journal of …, 2022 - Elsevier
Background It is not clear whether previous thyroid diseases influence the course and
outcomes of COVID-19. Methods The study is a part of a multicentric cohort of patients with …