Natural microbial communities are phylogenetically and metabolically diverse. In addition to
underexplored organismal groups 1 , this diversity encompasses a rich discovery potential …

Metagenomic sequencing has greatly improved our ability to profile the composition of
environmental and host-associated microbial communities. However, the dependency of most …

Ocean microbial communities strongly influence the biogeochemistry, food webs, and climate
of our planet. Despite recent advances in understanding their taxonomic and genomic …

Evaluating metagenomic software is key for optimizing metagenome interpretation and focus
of the Initiative for the Critical Assessment of Metagenome Interpretation (CAMI). The CAMI …

The deep sea, the largest ocean’s compartment, drives planetary-scale biogeochemical
cycling. Yet, the functional exploration of its microbial communities lags far behind other …

The role of the Arctic Ocean ecosystem in climate regulation may depend on the responses
of marine microorganisms to environmental change. We applied genome-resolved …

Health and resilience of the coral holobiont depend on diverse bacterial communities often
dominated by key marine symbionts of the Endozoicomonadaceae family. The factors …

Background Taxonomic profiling is a fundamental task in microbiome research that aims to
detect and quantify the relative abundance of microorganisms in biological samples. …

We present metaSNV, a tool for single nucleotide variant (SNV) analysis in metagenomic
samples, capable of comparing populations of thousands of bacterial and archaeal species. …

Microbiology depends on the availability of annotated microbial genomes for many applications.
Comparative genomics approaches have been a major advance, but consistent and …