As new sequencing technologies become cheaper and older ones disappear, laboratories
switch vendors and platforms. Validating the new setups is a crucial part of conducting …

The bacterioplankton diversity in large rivers has thus far been under‐sampled despite the
importance of streams and rivers as components of continental landscapes. Here, we present …

The HTSstation analysis portal is a suite of simple web forms coupled to modular analysis
pipelines for various applications of High-Throughput Sequencing including ChIP-seq, RNA-…

High-throughput DNA sequencing technologies are increasingly used for the metagenomic
characterisation of microbial biodiversity. However, basic issues, such as the choice of an …

Most free-living planktonic cells are streamlined and in spite of their limitations in functional
flexibility, their vast populations have radiated into a wide range of aquatic habitats. Here we …

The genomic loci occupied by RNA polymerase (RNAP) III have been characterized in
human culture cells by genome-wide chromatin immunoprecipitations, followed by deep …

Thousands of net-heterotrophic and strongly stratifying lakes dominate the boreal landscape.
Besides their central role as emitters of greenhouse gases, we have only recently begun to …

Background In molecular microbial ecology, massive sequencing is gradually replacing
classical fingerprinting techniques such as terminal-restriction fragment length polymorphism (T-…

Understanding the distribution of taxa and associated traits across different environments is
one of the central questions in microbial ecology. High-throughput sequencing (HTS) studies …

Some bacteria can be preserved over time in deep sediments where they persist either in
dormant or slow‐growing vegetative stages. Here, we hypothesized that such cells can be …