[HTML][HTML] Cross-reactive SARS-CoV-2 neutralizing antibodies from deep mining of early patient responses

…, D Pazeraitis, SB Surade, O Ashiru, L Crippa… - Frontiers in …, 2021 - frontiersin.org
Passive immunization using monoclonal antibodies will play a vital role in the fight against
COVID-19. The recent emergence of viral variants with reduced sensitivity to some current …

[HTML][HTML] Low-dose 7, 8-dihydroxyflavone administration after status epilepticus prevents epilepsy development

…, N Aziz, M Barbieri, D Bochicchio, L Crippa… - …, 2022 - Elsevier
Temporal lobe epilepsy often manifests months or even years after an initial epileptogenic
insult (eg, stroke, trauma, status epilepticus) and, therefore, may be preventable. However, no …

Deep mining of early antibody response in COVID-19 patients yields potent neutralisers and reveals high level of convergence

…, D Pazeraitis, SB Surade, O Ashiru, L Crippa… - bioRxiv, 2020 - biorxiv.org
Passive immunisation using monoclonal antibodies will play a vital role in the fight against
COVID-19. Until now, the majority of anti-SARS-CoV-2 antibody discovery efforts have relied …

Structural basis for broad coronavirus neutralization (preprint)

…, C Maas, T Renne, SB Surade, O Ashiru, L Crippa… - 2020 - pesquisa.bvsalud.org
Three highly pathogenic {beta}-coronaviruses crossed the animal-to-human species barrier
in the past two decades SARS-CoV, MERS-CoV and SARS-CoV-2. SARSCoV-2 has …

Non-covalent TMPRSS2 inhibitors identified from virtual screening (preprint)

…, C Maas, T Renne, SB Surade, O Ashiru, L Crippa… - 2020 - pesquisa.bvsalud.org
The SARS-CoV-2 pandemic has prompted researchers to pivot their efforts to finding anti-viral
compounds and vaccines. In this study, we focused on the human host cell …

Environmental Dependence of the Structure of the C-terminal Domain of the SARS-CoV-2 Envelope Protein (preprint)

…, C Maas, T Renne, SB Surade, O Ashiru, L Crippa… - 2020 - pesquisa.bvsalud.org
The SARS-CoV-2 envelope protein (E) is involved in a broad spectrum of functions in the
cycle of the virus, including assembly, budding, envelope formation, and pathogenesis. To …

Design of Specific Primer Set for Detection of B. 1.1. 7 SARS-CoV-2 Variant using Deep Learning (preprint)

…, C Maas, T Renne, SB Surade, O Ashiru, L Crippa… - 2020 - pesquisa.bvsalud.org
The SARS-CoV-2 variant B. 1.1. 7 lineage, also known as clade GR from Global Initiative on
Sharing All Influenza Data (GISAID), Nextstrain clade 20B, or Variant Under Investigation in …

Cerebral ventricle sites involved in the central hypertensive response to acetylcholine in unanesthetized rats

VL Peres-Polon, GE Crippa… - Ciênc. cult.(Säo Paulo), 1995 - pesquisa.bvsalud.org
It is well known that the injection of acetylcholine (ACh) into the lateral ventricles of the brain
(ICV) causes blood pressure increases in unanesthetized rats. However, the actual brain …

The consolidated European synthesis of CO2 emissions and removals for EU27 and UK: 1990-2018

…, S Efisio, Q Chunjing, P Roberto, G Dirk, P Lucia… - 2020 - agris.fao.org
Reliable quantification of the sources and sinks of atmospheric carbon dioxide (CO2), including
that of their trends and uncertainties, is essential to monitoring the progress in mitigating …

[HTML][HTML] The consolidated European synthesis of CO2 emissions and removals for EU27 and UK: 1990–2018

…, D Günther, L Perugini, M Crippa… - Earth System …, 2020 - essd.copernicus.org
Reliable quantification of the sources and sinks of atmospheric carbon dioxide (CO 2 ),
including that of their trends and uncertainties, is essential to monitoring the progress in …