[HTML][HTML] The clinically approved antiviral drug sofosbuvir inhibits Zika virus replication

…, EP Nunes, DA Tschoeke, L Leomil… - Scientific reports, 2017 - nature.com
Zika virus (ZIKV) is a member of the Flaviviridae family, along with other agents of clinical
significance such as dengue (DENV) and hepatitis C (HCV) viruses. Since ZIKV causes …

Insights on the freshwater microbiomes metabolic changes associated with the world's largest mining disaster

…, LR Appolinario, AC Soares, L Leomil… - Science of the Total …, 2019 - Elsevier
To evaluate the impacts of the Fundão tailings dam failure (Minas Gerais, Brazil) on water
quality of the Doce River, we analyzed metagenomics and physicochemical parameters …

Cultures of the Marine Bacterium Pseudovibrio denitrificans Ab134 Produce Bromotyrosine-Derived Alkaloids Previously Only Isolated from Marine Sponges

KJ Nicacio, LP Ióca, AM Fróes, L Leomil… - Journal of natural …, 2017 - ACS Publications
Herein we report the isolation and spectroscopic identification of fistularin-3 (1), 11-hydroxyaerothionin
(2), and verongidoic acid (3), as well as the UPLC-HRMS detection of aerothionin …

Development of standard methods for Zika virus propagation, titration, and purification

…, LM Meuren, DA Tschoeke, L Leomil… - Journal of virological …, 2017 - Elsevier
The emergence of Zika virus (ZIKV) infection has stimulated several research groups to study
and collaborate to understand virus biology and pathogenesis. These efforts may assist …

[HTML][HTML] Occurrence of harmful cyanobacteria in drinking water from a severely drought-impacted semi-arid region

…, M Lopes-Ferreira, LM Vidal, L Leomil… - Frontiers in …, 2018 - frontiersin.org
Harmful cyanobacterial blooms have become increasingly common in freshwater ecosystems
in recent decades, mainly due to eutrophication and climate change. Water becomes …

Clonal Relationship among Atypical Enteropathogenic Escherichia coli Strains Isolated from Different Animal Species and Humans

RA Moura, MP Sircili, L Leomil, MH Matté… - Applied and …, 2009 - Am Soc Microbiol
Forty-nine typical and atypical enteropathogenic Escherichia coli (EPEC) strains belonging
to different serotypes and isolated from humans, pets (cats and dogs), farm animals (bovines, …

Guarana (Paullinia cupana var. sorbilis), an anciently consumed stimulant from the Amazon rain forest: the seeded-fruit transcriptome

…, POA Acosta, JS Batista, MEMT Walter, L Leomil… - Plant cell reports, 2008 - Springer
Guarana (Paullinia cupana var. sorbilis) is a plant native to the central Amazon basin. Roasted
seed extracts have been used as medicinal beverages since pre-Colombian times, due …

[HTML][HTML] Emergence of the East-Central-South-African genotype of Chikungunya virus in Brazil and the city of Rio de Janeiro may have occurred years before …

…, PT Bozza, FA Bozza, DA Tschoeke, L Leomil… - Scientific Reports, 2019 - nature.com
Brazil, which is hyperendemic for dengue virus (DENV), has had recent Zika (ZIKV) and (CHIKV)
Chikungunya virus outbreaks. Since March 2016, CHIKV is the arbovirus infection most …

[HTML][HTML] The deep-sea microbial community from the Amazonian basin associated with oil degradation

ME Campeão, L Reis, L Leomil, L de Oliveira… - Frontiers in …, 2017 - frontiersin.org
One consequence of oil production is the possibility of unplanned accidental oil spills; therefore,
it is important to evaluate the potential of indigenous microorganisms (both prokaryotes …

Collapse of scallop Nodipecten nodosus production in the tropical Southeast Brazil as a possible consequence of global warming and water pollution

…, C Chueke, M de Lima Hilário, M Lima, L Leomil… - Science of The Total …, 2023 - Elsevier
Mollusc rearing is a relevant global socioeconomic activity. However, this activity has faced
severe problems in the last years in southeast Brazil. The mariculture scallop production …