User profiles for Luciano Abreu Brito
 | Luciano Abreu BritoPós-Doc, Universidade de São Paulo Verified email at usp.br Cited by 876 |
Exomic variants of an elderly cohort of Brazilians in the ABraOM database
Brazilians are highly admixed with ancestry from Europe, Africa, America, and Asia and yet
still underrepresented in genomic databanks. We hereby present a collection of exomic …
still underrepresented in genomic databanks. We hereby present a collection of exomic …
[HTML][HTML] Global and local ancestry modulate APOE association with Alzheimer's neuropathology and cognitive outcomes in an admixed sample
Dementia is more prevalent in Blacks than in Whites, likely due to a combination of environmental
and biological factors. Paradoxically, clinical studies suggest an attenuation of APOE …
and biological factors. Paradoxically, clinical studies suggest an attenuation of APOE …
[PDF][PDF] Genetics and management of the patient with orofacial cleft
Cleft lip or palate (CL/P) is a common facial defect present in 1: 700 live births and results in
substantial burden to patients. There are more than 500 CL/P syndromes described, the …
substantial burden to patients. There are more than 500 CL/P syndromes described, the …
[HTML][HTML] Differential methylation is associated with non-syndromic cleft lip and palate and contributes to penetrance effects
Non-syndromic cleft lip and/or palate (NSCLP) is a common congenital malformation with a
multifactorial model of inheritance. Although several at-risk alleles have been identified, they …
multifactorial model of inheritance. Although several at-risk alleles have been identified, they …
[HTML][HTML] Genetics and genomics in Brazil: a promising future
…, VE de Faria Ferraz, LA Brito - Molecular genetics & …, 2014 - ncbi.nlm.nih.gov
Medical Genetics has a recent history in Brazil and started out as a research program in
Human Genetics during the 1950s, mainly by a shift in work of Brazilian scientists from genetic …
Human Genetics during the 1950s, mainly by a shift in work of Brazilian scientists from genetic …
Rare variants in the epithelial cadherin gene underlying the genetic etiology of nonsyndromic cleft lip with or without cleft palate
LA Brito, GL Yamamoto, S Melo, C Malcher… - Human …, 2015 - Wiley Online Library
Nonsyndromic orofacial cleft (NSOFC) is a complex disease of still unclear genetic etiology.
To investigate the contribution of rare epithelial cadherin (CDH1) gene variants to NSOFC, …
To investigate the contribution of rare epithelial cadherin (CDH1) gene variants to NSOFC, …
[HTML][HTML] A novel saliva RT-LAMP workflow for rapid identification of COVID-19 cases and restraining viral spread
Rapid diagnostics is pivotal to curb SARS-CoV-2 transmission, and saliva has emerged as a
practical alternative to naso/oropharyngeal (NOP) specimens. We aimed to develop a direct …
practical alternative to naso/oropharyngeal (NOP) specimens. We aimed to develop a direct …
Region 8q24 is a susceptibility locus for nonsyndromic oral clefting in Brazil
LA Brito, LMR Paranaiba, CFS Bassi… - … Research Part A …, 2012 - Wiley Online Library
BACKGROUND Nonsyndromic cleft lip with or without cleft palate is a relatively common
craniofacial defect with multifactorial inheritance. The association of the rs987525 single …
craniofacial defect with multifactorial inheritance. The association of the rs987525 single …
[HTML][HTML] The influence of population stratification on genetic markers associated with type 1 diabetes
Ethnic admixtures may interfere with the definition of type 1 diabetes (T1D) risk determinants.
The role of HLA, PTPN22, INS-VNTR, and CTLA4 in T1D predisposition was analyzed in …
The role of HLA, PTPN22, INS-VNTR, and CTLA4 in T1D predisposition was analyzed in …
[PDF][PDF] Polymorphisms at regions 1p22. 1 (rs560426) and 8q24 (rs1530300) are risk markers for nonsyndromic cleft lip and/or palate in the Brazilian population
E Bagordakis, LM Paranaiba, LA Brito… - Am J Med Genet …, 2013 - academia.edu
Recent genetic risk factors for nonsyndromic cleft lip and/or palate (NSCL/P) have been
identified in genome-wide association studies (GWAS), however, few of them have been …
identified in genome-wide association studies (GWAS), however, few of them have been …