User profiles for Lucius S. Fekonja

Lucius S. Fekonja

PostDoc Charité Neurosurgery
Verified email at charite.de
Cited by 586

[HTML][HTML] Tractography dissection variability: What happens when 42 groups dissect 14 white matter bundles on the same dataset?

…, G Lerma-Usabiaga, L Roitman, LS Fekonja… - Neuroimage, 2021 - Elsevier
White matter bundle segmentation using diffusion MRI fiber tractography has become the
method of choice to identify white matter fiber pathways in vivo in human brains. However, like …

[HTML][HTML] Towards a tractography-based risk stratification model for language area associated gliomas

…, R Schilling, I Bährend, LL Silva, LS Fekonja… - NeuroImage: Clinical, 2021 - Elsevier
Objectives Injury to major white matter pathways during language-area associated glioma
surgery often leads to permanent loss of neurological function. The aim was to establish …

Metastatic dissemination patterns of different primary tumors to the spine and other bones

JS Onken, LS Fekonja, R Wehowsky… - Clinical & experimental …, 2019 - Springer
Metastatic spine disease (MSD) is a severe event in cancer patients. Experimental data
indicate that bone metastasis is mostly mediated by blood flow-dependent, passive arrest of …

[HTML][HTML] Detecting corticospinal tract impairment in tumor patients with fiber density and tensor-based metrics

LS Fekonja, Z Wang, DB Aydogan, T Roine… - Frontiers in …, 2021 - frontiersin.org
Tumors infiltrating the motor system lead to significant disability, often caused by corticospinal
tract injury. The delineation of the healthy-pathological white matter (WM) interface area, …

Improved prediction of glioma‐related aphasia by diffusion MRI metrics, machine learning, and automated fiber bundle segmentation

…, P Vajkoczy, C Lippert, T Picht, LS Fekonja - Human Brain …, 2023 - Wiley Online Library
White matter impairments caused by gliomas can lead to functional disorders. In this study,
we predicted aphasia in patients with gliomas infiltrating the language network using …

Role of interhemispheric connectivity in recovery from postoperative supplementary motor area syndrome in glioma patients

MS Tuncer, LS Fekonja, S Ott, A Pfnür, AG Karbe… - Journal of …, 2022 - thejns.org
OBJECTIVE Surgical resection of gliomas involving the supplementary motor area (SMA)
frequently results in SMA syndrome, a symptom complex characterized by transient akinesia …

[HTML][HTML] Lesion-symptom mapping of language impairments in patients suffering from left perisylvian gliomas

LS Fekonja, Z Wang, L Doppelbauer, P Vajkoczy… - cortex, 2021 - Elsevier
Brain tumors cause local structural impairments of the cerebral network. Moreover, brain
tumors can also affect functional brain networks more distant from the lesion. In this study, we …

[HTML][HTML] Support vector machine based aphasia classification of transcranial magnetic stimulation language mapping in brain tumor patients

…, F Pulvermüller, E Ntemou, P Vajkoczy, LS Fekonja… - NeuroImage: Clinical, 2021 - Elsevier
Repetitive TMS (rTMS) allows for non-invasive and transient disruption of local neuronal
functioning. We used machine learning approaches to assess whether brain tumor patients can …

[HTML][HTML] Tractography-based navigated TMS language mapping protocol

…, H Schneider, P Vajkoczy, T Picht, LS Fekonja - Frontiers in …, 2022 - frontiersin.org
This study explores the feasibility of implementing a tractography-based navigated transcranial
magnetic stimulation (nTMS) language mapping protocol targeting cortical terminations …

Zfp580 inactivation as a new therapeutic target to enhance recovery after stroke in mice

…, S Mueller, SP Koch, J An, LS Fekonja… - Journal of Cerebral …, 2023 - journals.sagepub.com
Paracrine cerebral Interleukin 6 (Il6) is relevant for stroke recovery, but systemic Il6 elevation
may worsen outcome. Hence, paracrine Il6 response modulation within the neurovascular …