The NONO protein has been characterized as an important transcriptional regulator in
diverse cellular contexts. Here we show that loss of NONO function is a likely cause of human …

Meiotic recombination rates vary across the genome, often involving localized crossover
hotspots and coldspots. Studying the molecular basis and mechanisms underlying this variation …

The SS18-SSX fusion drives oncogenic transformation in synovial sarcoma by bridging
SS18, a member of the mSWI/SNF (BAF) complex, to Polycomb repressive complex 1 (PRC1) …

Various lines of evidence suggest a mechanistic role for altered cAMP‐CREB (cAMP response
element ‐ binding protein) signaling in depressive and affective disorders. However, the …

Circadian clocks are present in most cells and are essential for maintenance of daily
rhythms in physiology, mood, and cognition. Thus, not only neurons of the central circadian …

Recent years have seen spectacular advances in the field of circadian biology. These have
attracted the interest of researchers in many fields, including endocrinology, neurosciences, …

10.7554/eLife.24994.001 The importance of natural gene expression variation for human
behavior is undisputed, but its impact on circadian physiology remains mostly unexplored. …

A biological “circadian” clock governs nearly all aspects of mammalian behavior and physiology.
This control extends from activities of entire organ systems down to individual cells, all …

The SS18-SSX fusion drives oncogenic transformation in synovial sarcoma by bridging SS18,
a member of mSWI/SNF complex, to Polycomb repressive complex 1 (PRC1) target genes…

Author response: The genomic landscape of human cellular circadian variation points to a novel
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