Most proteomic studies use liquid chromatography coupled to tandem mass spectrometry to
identify and quantify the peptides generated by the proteolysis of a biological sample. …

Over the past few years, media have popularized the story of the “children of the moon” who
must remain in the dark and avoid exposure to sunlight. 1r3 These children suffer from a …

Many research questions in fields such as personalized medicine, drug screens or systems
biology depend on obtaining consistent and quantitatively accurate proteomics data from …

… Ludovic Gillet … Hannes L Röst, George Rosenberger, Pedro Navarro, Ludovic Gillet, Saša
M Miladinović, Olga T Schubert, Ben C Collins, Lars Malmström & Ruedi … Ludovic Gillet …

Proteins constitute a key class of molecular components that perform essential biochemical
reactions in living cells. Whether the aim is to extensively characterize a given protein or to …

Clinical specimens are each inherently unique, limited and nonrenewable. Small samples
such as tissue biopsies are often completely consumed after a limited number of analyses. …

Protein complexes and protein interaction networks are essential mediators of most
biological functions. Complexes supporting transient functions such as signal transduction …

The degree and the origins of quantitative variability of most human plasma proteins are
largely unknown. Because the twin study design provides a natural opportunity to estimate the …

Targeted proteomics by selected/multiple reaction monitoring (S/MRM) or, on a larger scale,
by SWATH (sequential window acquisition of all theoretical spectra) MS (mass spectrometry…

Consistent and accurate quantification of proteins by mass spectrometry (MS)-based
proteomics depends on the performance of instruments, acquisition methods and data analysis …