Dictyostelium discoideum (DD), an extensively studied model organism for cell and developmental
biology, belongs to the most derived group 4 of social amoebas, a clade of altruistic …

Background The social amoebae (Dictyostelia) are a diverse group of Amoebozoa that
achieve multicellularity by aggregation and undergo morphogenesis into fruiting bodies with …

The use of simple hosts such as Dictyostelium discoideum in the study of host pathogen
interactions offers a number of advantages and has steadily increased in recent years. Infection-…

Background Medium density DNA microchips that carry a collection of probes for a broad
spectrum of pathogens, have the potential to be powerful tools for simultaneous species …

Environmental bacteria of the genus Legionella naturally parasitize free-living amoebae.
Upon inhalation of bacteria-laden aerosols, the opportunistic pathogens grow intracellularly in …

The genome of the lower eukaryote Dictyostelium discoideum comprises six chromosomes.
Here we report the sequence of the largest, chromosome 2, which at 8 megabases (Mb) …

Dictyostelium discoideum offers unique advantages for studying fundamental cellular
processes, host–pathogen interactions as well as the molecular causes of human diseases. The …

We have identified a DNA methyltransferase of the Dnmt2 family in Dictyostelium that was
denominated DnmA. Expression of the dnmA gene is downregulated during the …

Differential gene expression of Dictyostelium discoideum after infection with Legionella
pneumophila was investigated using DNA microarrays. Investigation of a 48 h time course of …

Infection of Dictyostelium discoideum with Legionella pneumophila resulted in a large number
of differentially regulated genes among them three core autophagy genes, ATG8, ATG9 …