User profiles for Luis Miguel Real
 | Luis M. RealDpto. Bioquímica Médica, Biología Molecular e Inmunología. Universidad de Sevilla Verified email at us.es Cited by 8080 |
[HTML][HTML] The membrane-spanning 4-domains, subfamily A (MS4A) gene cluster contains a common variant associated with Alzheimer's disease
Background In order to identify novel loci associated with Alzheimer's disease (AD), we
conducted a genome-wide association study (GWAS) in the Spanish population. Methods We …
conducted a genome-wide association study (GWAS) in the Spanish population. Methods We …
Chromosome loss is the most frequent mechanism contributing to HLA haplotype loss in human tumors
Loss of heterozygosity (LOH) in the short arm of chromosome 6 (6p) was detected in samples
obtained from colon (13.8%), larynx (17.6%) and melanoma (15.3%) tumors. The parallel …
obtained from colon (13.8%), larynx (17.6%) and melanoma (15.3%) tumors. The parallel …
CAPN10 Alleles Are Associated with Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is characterized by chronic anovulation infertility,
hyperandrogenemia, and frequently insulin resistance. This study investigated whether …
hyperandrogenemia, and frequently insulin resistance. This study investigated whether …
Incidence and natural history of hepatitis E virus coinfection among HIV-infected patients
Objectives: To know the prevalence, incidence and factors associated with hepatitis E virus (HEV)
infection in HIV-infected individuals in Spain, as well as to provide information on the …
infection in HIV-infected individuals in Spain, as well as to provide information on the …
Specific CAPN10 Gene Haplotypes Influence the Clinical Profile of Polycystic Ovary Patients
…, JJ Galán, JA Herreros, LM Real… - The Journal of …, 2003 - academic.oup.com
Recently, several research groups have evaluated CAPN10 gene in polycystic ovarian
syndrome (PCOS) patients and other phenotypes, including hirsutism or intermediate …
syndrome (PCOS) patients and other phenotypes, including hirsutism or intermediate …
[HTML][HTML] A method for detecting epistasis in genome-wide studies using case-control multi-locus association analysis
…, JJ Galan, FJ Moron, R Ramirez-Lorca, LM Real… - BMC genomics, 2008 - Springer
Background The difficulty in elucidating the genetic basis of complex diseases roots in the
many factors that can affect the development of a disease. Some of these genetic effects may …
many factors that can affect the development of a disease. Some of these genetic effects may …
[HTML][HTML] Multiomics integrative analysis identifies APOE allele-specific blood biomarkers associated to Alzheimer's disease etiopathogenesis
Alzheimer’s disease (AD) is the most common form of dementia, currently affecting 35 million
people worldwide. Apolipoprotein E (APOE) ε4 allele is the major risk factor for sporadic, …
people worldwide. Apolipoprotein E (APOE) ε4 allele is the major risk factor for sporadic, …
Association of NOS3 gene with metabolic syndrome in hypertensive patients
Recent data from animal models indicate that the eNOS null mice present a phenotype that
resemble the human metabolic syndrome (hypertension, insulin resistance and …
resemble the human metabolic syndrome (hypertension, insulin resistance and …
Expression of HLA G in human tumors is not a frequent event
L Miguel Real, T Cabrera, A Collado… - … journal of cancer, 1999 - Wiley Online Library
Expression of HLA G may be a way for tumor cells to escape immuno‐surveillance. HLA G is
selectively expressed by extravillous trophoblast in the human placenta, a tissue that does …
selectively expressed by extravillous trophoblast in the human placenta, a tissue that does …
[HTML][HTML] The ubiquitin proteasome system in neuromuscular disorders: moving beyond movement
Neuromuscular disorders (NMDs) affect 1 in 3000 people worldwide. There are more than
150 different types of NMDs, where the common feature is the loss of muscle strength. These …
150 different types of NMDs, where the common feature is the loss of muscle strength. These …