Natural products from microbes have provided humans with beneficial antibiotics for millennia.
However, a decline in the pace of antibiotic discovery exerts pressure on human health …

The complete genome sequence of the original isolate of the model actinomycete
Streptomyces lividans 66, also referred to as 1326, was deciphered after a combination of next-…

Neuropeptides are a diverse class of signaling molecules in metazoans. They occur in all
animals with a nervous system and also in neuron-less placozoans. However, their origin has …

Neuropeptides are a diverse class of intercellular signalling molecules that mediate neuronal
regulation of many physiological and behavioural processes. Recent advances in genome/…

Somatostatin (SS) and allatostatin-C (ASTC) are structurally and evolutionarily related
neuropeptides that act as inhibitory regulators of physiological processes in mammals and insects…

Pelagic larval stages are widespread across animals, yet it is unclear whether larvae were
present in the last common ancestor of animals or whether they evolved multiple times due to …

ASIC channels are bilaterian proton-gated sodium channels belonging to the large and
functionally-diverse Deg/ENaC family that also includes peptide- and mechanically-gated …

Neuropeptides are diverse signaling molecules in animals commonly acting through G-protein
coupled receptors (GPCRs). Neuropeptides and their receptors underwent extensive …

Neuropeptide signalling systems comprising peptide ligands and cognate receptors are
evolutionarily ancient regulators of physiology and behaviour. However, there are challenges …

Neuropeptides are one of the largest and most diverse families of signaling molecules in
animals and, accordingly, they regulate many physiological processes and behaviors. Genome …