The mother as most important risk factor for colonization of very low birth weight (VLBW) infants with extended-spectrum β-lactamase-producing Enterobacteriaceae …

LA Denkel, F Schwab, A Kola, R Leistner… - Journal of …, 2014 - academic.oup.com
Objectives This study aimed to determine the prevalence of and risk factors for colonization
with extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E) and methicillin…

[HTML][HTML] Protective effect of dual-strain probiotics in preterm infants: a multi-center time series analysis

LA Denkel, F Schwab, L Garten, C Geffers… - PLoS …, 2016 - journals.plos.org
Objective To determine the effect of dual-strain probiotics on the development of necrotizing
enterocolitis (NEC), mortality and nosocomial bloodstream infections (BSI) in preterm infants …

[HTML][HTML] Methionine Sulfoxide Reductases Are Essential for Virulence of Salmonella Typhimurium

LA Denkel, SA Horst, SF Rouf, V Kitowski, OM Böhm… - PloS one, 2011 - journals.plos.org
Production of reactive oxygen species represents a fundamental innate defense against
microbes in a diversity of host organisms. Oxidative stress, amongst others, converts peptidyl …

Thiol Peroxidase Protects Salmonella enterica from Hydrogen Peroxide Stress In Vitro and Facilitates Intracellular Growth

SA Horst, T Jaeger, LA Denkel, SF Rouf… - Journal of …, 2010 - Am Soc Microbiol
At present, Salmonella is considered to express two peroxiredoxin-type peroxidases, TsaA
and AhpC. Here we describe an additional peroxiredoxin, Tpx, in Salmonella enterica and …

[HTML][HTML] Admission prevalence of colonization with third-generation cephalosporin-resistant Enterobacteriaceae and subsequent infection rates in a German …

…, J Zweigner, P Gastmeier, LA Denkel - PloS one, 2018 - journals.plos.org
Background Many patients admitted to a hospital are already colonized with multi-drug
resistant organisms (MDRO) including third-generation cephalosporin-resistant …

[HTML][HTML] Clinical Evidence for the Use of Octenidine Dihydrochloride to Prevent Healthcare-Associated Infections and Decrease Staphylococcus aureus Carriage or …

R Köck, L Denkel, AT Feßler, R Eicker, A Mellmann… - Pathogens, 2023 - mdpi.com
Background: The antiseptic agent octenidine dihydrochloride (OCT) is used for skin
preparation, for Staphylococcus aureus decolonization, and within bundles for the prevention of …

Split k-mer analysis compared to cgMLST and SNP-based core genome analysis for detecting transmission of vancomycin-resistant enterococci: results from routine …

…, O Schwengers, F Schwab, L Denkel… - Microbial …, 2023 - microbiologyresearch.org
The increase of Vancomycin-resistant Enterococcus faecium (VREfm) in recent years has
been partially attributed to the rise of specific clonal lineages, which have been identified …

[HTML][HTML] Prevalence and risk factors of colonisation with vancomycin-resistant Enterococci faecium upon admission to Germany's largest university hospital

…, M Kipnis, AC Boldt, M Behnke, LA Denkel… - GMS Hygiene and …, 2021 - ncbi.nlm.nih.gov
Background: Hospital-acquired infections due to vancomycin-resistant enterococci (VRE) are
emerging globally. The aims of our study were to estimate VRE colonisation prevalence in …

[HTML][HTML] Effects and feasibility of hyperthermic baths in comparison to exercise as add-on treatment to usual care in depression: a randomised, controlled pilot study

J Naumann, I Kruza, L Denkel, G Kienle, R Huber - BMC psychiatry, 2020 - Springer
Background Limitations of current therapy of depression highlight the need for an immediately
available, easily implementable add-on treatment option with high acceptance from …

[HTML][HTML] Effect of antiseptic bathing with chlorhexidine or octenidine on central line–associated bloodstream infections in intensive care patients: a cluster-randomized …

LA Denkel, F Schwab, J Clausmeyer, M Behnke… - Clinical Microbiology …, 2022 - Elsevier
Objectives Our study aimed to compare the effect of daily bathing with chlorhexidine, octenidine,
or water and soap (routine care = control) on central line (CL)–associated bloodstream …