[HTML][HTML] Investigation of adenosine A1 receptor-mediated β-arrestin 2 recruitment using a split-luciferase assay

L Saecker, H Häberlein, S Franken - Frontiers in Pharmacology, 2023 - frontiersin.org
Background: Adenosine A1 receptor (A 1 AR) plays a prominent role in neurological and
cardiac diseases and inflammatory processes. Its endogenous ligand adenosine is known to …

Microglial PD‐1 stimulation by astrocytic PD‐L1 suppresses neuroinflammation and Alzheimer's disease pathology

…, C Kummer, H Sarlus, A Griep, A Vieira‐Saecker… - The EMBO …, 2021 - embopress.org
Chronic neuroinflammation is a pathogenic component of Alzheimer’s disease (AD) that may
limit the ability of the brain to clear amyloid deposits and cellular debris. Tight control of the …

[HTML][HTML] Herpes simplex virus type 1 infection of the central nervous system: insights into proposed interrelationships with neurodegenerative disorders

LF Duarte, MA Farías, DM Álvarez… - Frontiers in Cellular …, 2019 - frontiersin.org
Herpes simplex virus type 1 (HSV-1) is highly prevalent in humans and can reach the brain
without evident clinical symptoms. Once in the central nervous system (CNS), the virus can …

[PDF][PDF] PHOTOS IMFS/Hannelore Förster, German Council of Economic Experts, Kronberger Kreis

TW Adorno-Platz - 2021 - d-nb.info
Luisa Lambertini is a Professor at the Ecole Polytechnique Fédérale de Lausanne, where
Luisa Lambertini is a member of the Executive Committee of the International Banking, …

[PDF][PDF] Mainz Media Institute

TW Adorno-Platz, K Kreis - 2020 - imfs-frankfurt.de
… Petra Geraats, Luisa Lambertini and Maik Wolters had already been involved in IMFS activities
… Johanna Saecker joined the Chair of Financial Markets and Macroeconomics in October …

[HTML][HTML] Spinocerebellar ataxia in the Italian Spinone dog is associated with an intronic GAA repeat expansion in ITPR1

OP Forman, L De Risio, K Matiasek, S Platt… - Mammalian …, 2015 - Springer
Spinocerebellar ataxia in the Italian Spinone dog breed is characterised by a progressive
gait abnormality that manifests from approximately 4 months of age. The disorder shows an …

[HTML][HTML] Nucleocytoplasmic shuttling activity of ataxin-3

S Macedo-Ribeiro, L Cortes, P Maciel, AL Carvalho - PloS one, 2009 - journals.plos.org
<p>Spinocerebellar ataxia type-3, also known as Machado-Joseph Disease (MJD), is one
of many inherited neurodegenerative disorders caused by polyglutamine-encoding CAG …

The Savage Innocents--Part 2: On the Road with Parsifal, Butterfly, the Widow, and the Girl

J McPherson - The Opera Quarterly, 2003 - muse.jhu.edu
Although the Castle Square banner continued to fly in several cities for a few more years,
New York knew it no more after May 1900 for the simple reason that, as the Times put it,“The …

Inflammation and metabolism in tissue repair and regeneration

SA Eming, TA Wynn, P Martin - Science, 2017 - science.org
Tissue repair after injury is a complex, metabolically demanding process. Depending on the
tissue’s regenerative capacity and the quality of the inflammatory response, the outcome is …

Electrophilic warhead-based design of compounds preventing NLRP3 inflammasome-dependent pyroptosis

M Cocco, D Garella, A Di Stilo, E Borretto… - Journal of Medicinal …, 2014 - ACS Publications
Pyroptosis is a caspase-1-dependent pro-inflammatory form of programmed cell death
implicated in the pathogenesis of autoinflammatory diseases as well as in disorders …