Ultraviolet-B (UV-B) radiation present in sunlight is an important trigger of photomorphogenic
acclimation and stress responses in sessile land plants. Although numerous moss species …

10.7554/eLife.05856.001 Although it is often tacitly assumed that gene regulatory
interactions are finely tuned, how accurate gene regulation could evolve from a state without …

Identification of novel antibiotics remains a major challenge for drug discovery. The present
study explores use of phenotypic readouts beyond classical antibacterial growth inhibition …

Determining the molecular changes that give rise to functional innovations is a major unresolved
problem in biology. The paucity of examples has served as a significant hindrance in …

The moss P hyscomitrella patens is an important model organism for studying plant evolution,
development, physiology and biotechnology. Here we have generated microarray gene …

Across the plant kingdom, phytochrome (PHY) photoreceptors play an important role during
adaptive and developmental responses to light. In Arabidopsis thaliana, light-activated …

Mutations in glucocerebrosidase cause the lysosomal storage disorder Gaucher’s disease
and are the most common risk factor for Parkinson’s disease. Therapies to restore the enzyme…

Background Due to increased resistance and safety concerns with insecticide-based
pediculicides, there is growing demand for head lice treatments with a physical mode of action. …

MAPK inhibitors (MAPKi) remain an important component of the standard of care for metastatic
melanoma. However, acquired resistance to these drugs limits their therapeutic benefit. …

In Immersion Into Noise schreibt Joseph Nechvatal, Noise-Musik könne ein Schwanken der
Wahrnehmung evozieren zwischen sich selbst unheimlich nahe sein und unglaublich weit …