The growth of gene and protein sequence information is currently so rapid that three-dimensional
structural information is lacking for the overwhelming majority of known proteins. In this …

Several nuclear activities and components are concentrated in discrete nuclear compartments.
To understand the functional significance of nuclear compartmentalization, knowledge on …

Covalently linked cell wall proteins (CWPs) of the dimorphic fungus Candida albicans are
implicated in virulence. We have carried out a comprehensive proteomic analysis of the …

Eukaryotic chromatin is organized into topologically constrained loops that are attached to
the nuclear matrix. The regions of DNA that interact with the matrix are called matrix …

The cell wall of yeast contains proteins that are covalently bound to the glycan network. These
cell wall proteins (CWPs) mediate cell-cell interactions and may be involved in cell wall …

We have isolated a monoclonal antibody, 5E10, that labels discrete spots in the interphase
nucleus. By immunoblotting mAb SE10 recognized predominantly a 126 kDa polypeptide …

The mitochondrial prohibitin complex consists of two subunits (PHB1 of 32 kD and PHB2 of
34 kD), assembled into a membrane‐associated supercomplex of approximately 1 MD. A …

We have investigated the spatial relationship between sites containing newly synthesized
RNA and domains containing proteins involved in transcription, such as RNA polymerase II …

A general method is described to sequester peptides containing azides from complex peptide
mixtures, aimed at facilitating mass spectrometric analysis to study different aspects of …

We compared the protein composition of the nuclear matrix isolated from several murine
embryonal carcinoma cells and mature tissues by two-dimensional gel electrophoresis. Two …