User profiles for Luiz C. Irber

Luiz Irber

Staff Bioinformatics Engineer, Ancestry
Verified email at ucdavis.edu
Cited by 1229

[HTML][HTML] Haplotype-phased synthetic long reads from short-read sequencing

JA Stapleton, J Kim, JP Hamilton, M Wu, LC Irber… - PloS one, 2016 - journals.plos.org
Next-generation DNA sequencing has revolutionized the study of biology. However, the short
read lengths of the dominant instruments complicate assembly of complex genomes and …

[HTML][HTML] Efficient cardinality estimation for k-mers in large DNA sequencing data sets: k-mer cardinality estimation

LC Irber Jr, CT Brown - biorxiv, 2016 - biorxiv.org
We present an open implementation of the HyperLogLog cardinality estimation sketch for
counting fixed-length substrings of DNA strings (“k-mers”). The HyperLogLog sketch …

[BOOK][B] Decentralizing indices for genomic data

LC Irber Jr - 2020 - search.proquest.com
Biology as a field is being transformed by the increasing availability of data, especially
genomic sequencing data. Computational methods that can adapt and take advantage of this …

[HTML][HTML] The khmer software package: enabling efficient nucleotide sequence analysis

…, C Pepe-Ranney, ZN Russ, E Schwarz, C Scott… - …, 2015 - ncbi.nlm.nih.gov
The khmer package is a freely available software library for working efficiently with fixed length
DNA words, or k-mers. khmer provides implementations of a probabilistic k-mer counting …

[HTML][HTML] Critical assessment of metagenome interpretation: the second round of challenges

…, J Kwan, N LaPierre, C Lemaitre, C Li… - Nature …, 2022 - nature.com
Evaluating metagenomic software is key for optimizing metagenome interpretation and focus
of the Initiative for the Critical Assessment of Metagenome Interpretation (CAMI). The CAMI …

sourmash: a library for MinHash sketching of DNA

CT Brown, L Irber - Journal of open source software, 2016 - joss.theoj.org
MinHash sketches provide a lightweight way to store “signatures” of large DNA or RNA
sequence collections, and then compare or search them using a Jaccard index. MinHash …

[HTML][HTML] Large-scale sequence comparisons with sourmash

NT Pierce, L Irber, T Reiter, P Brooks, CT Brown - F1000Research, 2019 - ncbi.nlm.nih.gov
The sourmash software package uses MinHash-based sketching to create “signatures”,
compressed representations of DNA, RNA, and protein sequences, that can be stored, searched…

Lightweight compositional analysis of metagenomes with FracMinHash and minimum metagenome covers

L Irber, PT Brooks, T Reiter, NT Pierce-Ward, MR Hera… - BioRxiv, 2022 - biorxiv.org
The identification of reference genomes and taxonomic labels from metagenome data underlies
many microbiome studies. Here we describe two algorithms for compositional analysis …

[HTML][HTML] Climate simulation and change in the Brazilian climate model

…, SN Figueroa, MC Costa, M Baptista, L Irber… - Journal of …, 2013 - journals.ametsoc.org
c. Model climatology and systematic errors … Doutriaux, C., and KE Tayler, cited 2011:
Climate Model Output Rewriter (CMOR). CMOR 2.0 Users Guide. [Available online at http://www2-pcmdi.llnl.gov/cmor/documentation/cmor-2-0-users-guide-html.] …

Streamlining data-intensive biology with workflow systems

…, PT Brooks, L Irber, SEK Joslin, CM Reid, C Scott… - …, 2021 - academic.oup.com
As the scale of biological data generation has increased, the bottleneck of research has
shifted from data generation to analysis. Researchers commonly need to build computational …