Most proteomic studies use liquid chromatography coupled to tandem mass spectrometry to
identify and quantify the peptides generated by the proteolysis of a biological sample. …

Selected reaction monitoring (SRM) is a targeted mass spectrometric method that is increasingly
used in proteomics for the detection and quantification of sets of preselected proteins at …

The data-independent acquisition (DIA) approach has recently been introduced as a novel
mass spectrometric method that promises to combine the high content aspect of shotgun …

Multiple reaction monitoring ( MRM ) has recently become the method of choice for targeted
quantitative measurement of proteins using mass spectrometry. The method, however, is …

MassIVE.quant is a repository infrastructure and data resource for reproducible quantitative
mass spectrometry–based proteomics, which is compatible with all mass spectrometry data …

Liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) is the main
method for high-throughput identification and quantification of peptides and inferred proteins. …

Targeted analysis of data‐independent acquisition (DIA) data is a powerful mass spectrometric
approach for comprehensive, reproducible and precise proteome quantitation. It requires …

Adoption of targeted mass spectrometry (MS) approaches such as multiple reaction monitoring
(MRM) to study biological and biomedical questions is well underway in the proteomics …

Comprehensive, reproducible and precise analysis of large sample cohorts is one of the
key objectives of quantitative proteomics. Here, we present an implementation of data-…

Comprehensive characterization of a proteome is a fundamental goal in proteomics. To
achieve saturation coverage of a proteome or specific subproteome via tandem mass …