[HTML][HTML] Within-sibship genome-wide association analyses decrease bias in estimates of direct genetic effects
Estimates from genome-wide association studies (GWAS) of unrelated individuals capture
effects of inherited variation (direct effects), demography (population stratification, assortative …
effects of inherited variation (direct effects), demography (population stratification, assortative …
No support for historical candidate gene or candidate gene-by-interaction hypotheses for major depression across multiple large samples
Objective: Interest in candidate gene and candidate gene-by-environment interaction hypotheses
regarding major depressive disorder remains strong despite controversy surrounding …
regarding major depressive disorder remains strong despite controversy surrounding …
Comparison of methods that use whole genome data to estimate the heritability and genetic architecture of complex traits
Multiple methods have been developed to estimate narrow-sense heritability, h 2 , using
single nucleotide polymorphisms (SNPs) in unrelated individuals. However, a comprehensive …
single nucleotide polymorphisms (SNPs) in unrelated individuals. However, a comprehensive …
Spontaneous bacterial peritonitis in asymptomatic outpatients with cirrhotic ascites
The prevalence and natural history of spontaneous bacterial peritonitis in asymptomatic
patients with ascites secondary to cirrhosis is unknown. From a prospectively recorded database…
patients with ascites secondary to cirrhosis is unknown. From a prospectively recorded database…
Population genomics of Populus trichocarpa identifies signatures of selection and adaptive trait associations
Forest trees are dominant components of terrestrial ecosystems that have global ecological
and economic importance. Despite distributions that span wide environmental gradients, …
and economic importance. Despite distributions that span wide environmental gradients, …
[HTML][HTML] Community specificity: life and afterlife effects of genes
Community-level genetic specificity results when individual genotypes or populations of the
same species support different communities. Our review of the literature shows that genetic …
same species support different communities. Our review of the literature shows that genetic …
[HTML][HTML] Mapped aboveground carbon stocks to advance forest conservation and recovery in Malaysian Borneo
Forest carbon stocks in rapidly developing tropical regions are highly heterogeneous, which
challenges efforts to develop spatially-explicit conservation actions. In addition to field-…
challenges efforts to develop spatially-explicit conservation actions. In addition to field-…
[HTML][HTML] A mirror code for protein-cholesterol interactions in the two leaflets of biological membranes
Cholesterol controls the activity of a wide range of membrane receptors through specific
interactions and identifying cholesterol recognition motifs is therefore critical for understanding …
interactions and identifying cholesterol recognition motifs is therefore critical for understanding …
Within-sibship GWAS improve estimates of direct genetic effects
Estimates from genome-wide association studies (GWAS) represent a combination of the
effect of inherited genetic variation (direct effects), demography (population stratification, …
effect of inherited genetic variation (direct effects), demography (population stratification, …
[HTML][HTML] High-resolution genetic mapping of allelic variants associated with cell wall chemistry in Populus
Background QTL cloning for the discovery of genes underlying polygenic traits has historically
been cumbersome in long-lived perennial plants like Populus. Linkage disequilibrium-…
been cumbersome in long-lived perennial plants like Populus. Linkage disequilibrium-…