Skeletal muscle phosphocreatine recovery in exercise-trained humans is dependent on O2availability

LJ Haseler, MC Hogan… - Journal of applied …, 1999 - journals.physiology.org
In skeletal muscle, phosphocreatine (PCr) recovery from submaximal exercise has become
a reliable and accepted measure of muscle oxidative capacity. During exercise, O 2 …

Human muscle performance and PCr hydrolysis with varied inspired oxygen fractions: a31P-MRS study

…, RS Richardson, LJ Haseler - Journal of Applied …, 1999 - journals.physiology.org
The purpose of this study was to use 31 P-magnetic resonance spectroscopy to examine
the relationships among muscle PCr hydrolysis, intracellular H + concentration accumulation, …

1H MRS in acute traumatic brain injury

BD Ross, T Ernst, R Kreis, LJ Haseler… - Journal of Magnetic …, 1998 - Wiley Online Library
The objective of this study was to demonstrate 1 H MR spectroscopy (MRS) changes in cerebral
metabolites after acute head trauma. Twenty‐five patients (12 children, 13 adults) were …

Reduced Mechanical Efficiency in Chronic Obstructive Pulmonary Disease but Normal Peak V̇o2 with Small Muscle Mass Exercise

…, BT Leek, TP Gavin, LJ Haseler… - American journal of …, 2004 - atsjournals.org
We studied six patients with chronic obstructive pulmonary disease (COPD) (FEV 1 = 1.1 ±
0.2 L, 32% of predicted) and six age- and activity level–matched control subjects while …

[HTML][HTML] Adenosine and its receptors in the heart: regulation, retaliation and adaptation

…, JN Peart, ME Reichelt, LJ Haseler - Biochimica et Biophysica …, 2011 - Elsevier
The purine nucleoside adenosine is an important regulator within the cardiovascular system,
and throughout the body. Released in response to perturbations in energy state, among …

Phosphocreatine hydrolysis during submaximal exercise: the effect of

LJ Haseler, RS Richardson… - Journal of applied …, 1998 - journals.physiology.org
There is evidence that the concentration of the high-energy phosphate metabolites may be
altered during steady-state submaximal exercise by the breathing of different fractions of …

Time course-dependent changes in the transcriptome of human skeletal muscle during recovery from endurance exercise: from inflammation to adaptive remodeling

…, KH Wagner, LJ Haseler… - Journal of Applied …, 2014 - journals.physiology.org
Reprogramming of gene expression is fundamental for skeletal muscle adaptations in response
to endurance exercise. This study investigated the time course-dependent changes in …

Effect of prolonged, heavy exercise on pulmonary gas exchange in athletes

…, TP Gavin, NM Siafakas, LJ Haseler… - Journal of Applied …, 1998 - journals.physiology.org
During maximal exercise, ventilation-perfusion inequality increases, especially in athletes.
The mechanism remains speculative. We hypothesized that, if interstitial pulmonary edema is …

Influence of exercise intensity and duration on functional and biochemical perturbations in the human heart

…, LJ Haseler, JJ Kavanagh, J Chan… - The Journal of …, 2016 - Wiley Online Library
Key points Strenuous endurance exercise induces transient functional and biochemical
cardiac perturbations that persist for 24–48 h. The magnitude and time‐course of exercise‐…

[HTML][HTML] Evaluation of a 7-gene genetic profile for athletic endurance phenotype in ironman championship triathletes

R Grealy, J Herruer, CLE Smith, D Hiller, LJ Haseler… - PloS one, 2015 - journals.plos.org
Polygenic profiling has been proposed for elite endurance performance, using an additive
model determining the proportion of optimal alleles in endurance athletes. To investigate this …