User profiles for Lunbo Tan
Lunbo TanErasmus MC Verified email at erasmusmc.nl Cited by 254 |
[HTML][HTML] The role of chemerin in metabolic and cardiovascular disease: a literature review of its physiology and pathology from a nutritional perspective
Chemerin is a novel adipokine that plays a major role in adipogenesis and lipid metabolism.
It also induces inflammation and affects insulin signaling, steroidogenesis and …
It also induces inflammation and affects insulin signaling, steroidogenesis and …
[HTML][HTML] Dietary supplementation of Astragalus polysaccharides enhanced immune components and growth factors EGF and IGF-1 in sow colostrum
L Tan, T Wei, A Yuan, J He, J Liu, D Xu… - Journal of Immunology …, 2017 - hindawi.com
Colostrum is the main external resource providing piglets with nutrients and maternal immune
molecules. Astragalus polysaccharides (APS) have been used as immunopotentiators in …
molecules. Astragalus polysaccharides (APS) have been used as immunopotentiators in …
[HTML][HTML] Placenta-specific drug delivery by trophoblast-targeted nanoparticles in mice
Rationale: The availability of therapeutics to treat pregnancy complications is severely lacking,
mainly due to the risk of harm to the fetus. In placental malaria, Plasmodium falciparum-…
mainly due to the risk of harm to the fetus. In placental malaria, Plasmodium falciparum-…
Placental trophoblast-specific overexpression of chemerin induces preeclampsia-like symptoms
Maternal circulating levels of the adipokine chemerin are elevated in preeclampsia, but its
origin and contribution to preeclampsia remain unknown. We therefore studied (1) placental …
origin and contribution to preeclampsia remain unknown. We therefore studied (1) placental …
Nanocapsule-mediated sustained H2 release in the gut ameliorates metabolic dysfunction-associated fatty liver disease
Z Jin, Y Sun, T Yang, L Tan, P Lv, Q Xu, G Tao, S Qin… - Biomaterials, 2021 - Elsevier
Metabolic dysfunction-associated fatty liver disease (MAFLD) is estimated to affect a quarter
of all population and represents a major health threat to all societies. Yet, currently no …
of all population and represents a major health threat to all societies. Yet, currently no …
[HTML][HTML] Transplacental Zika virus transmission in ex vivo perfused human placentas
…, M Broekhuizen, PPA Unger, L Tan… - PLoS Neglected …, 2022 - journals.plos.org
A Zika virus (ZIKV) infection during pregnancy can result in severe birth defects such as
microcephaly. To date, it is incompletely understood how ZIKV can cross the human placenta. …
microcephaly. To date, it is incompletely understood how ZIKV can cross the human placenta. …
[HTML][HTML] Adipokine chemerin overexpression in trophoblasts leads to dyslipidemia in pregnant mice: implications for preeclampsia
L Tan, Z Ouyang, Z Chen, F Sun, H Guo… - Lipids in Health and …, 2023 - Springer
Background The adipokine chemerin regulates adipogenesis and the metabolic function of
both adipocytes and liver. Chemerin is elevated in preeclamptic women, and overexpression …
both adipocytes and liver. Chemerin is elevated in preeclamptic women, and overexpression …
[HTML][HTML] Megalin, proton pump inhibitors and the renin–angiotensin system in healthy and pre-eclamptic placentas
Y Sun, L Tan, RI Neuman, M Broekhuizen… - International Journal of …, 2021 - mdpi.com
Soluble Fms-like tyrosine kinase-1 (sFlt-1) is increased in pre-eclampsia. The proton pump
inhibitor (PPI) lowers sFlt-1, while angiotensin increases it. To investigate whether PPIs lower …
inhibitor (PPI) lowers sFlt-1, while angiotensin increases it. To investigate whether PPIs lower …
Statins Prevent the Deleterious Consequences of Placental Chemerin Upregulation in Preeclampsia
L Tan, ACM Kluivers, EO Cruz-López… - …, 2024 - Am Heart Assoc
BACKGROUND: Chemerin, an inflammatory adipokine, is upregulated in preeclampsia,
and its placental overexpression results in preeclampsia-like symptoms in mice. Statins may …
and its placental overexpression results in preeclampsia-like symptoms in mice. Statins may …
Serum Chemerin As A Novel Biomarker For Preeclampsia Complications: Effects Of Statins On Its Release From The Placenta
L Tan, M Broekhuizen, RI Neuman… - …, 2022 - Am Heart Assoc
Background: The adipokine chemerin is increased in preeclampsia (PE), possibly because
it is released from the placenta. We aimed to evaluate the potential of chemerin as novel …
it is released from the placenta. We aimed to evaluate the potential of chemerin as novel …