Background While the leading symptoms during coronavirus disease 2019 (COVID-19) are
acute and the majority of patients fully recover, a significant fraction of patients now …

As exemplified by the ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
pandemic, there is a strong demand for rapid high-throughput isolation pipelines to …

The SARS-CoV-2 pandemic has unprecedented implications for public health, social life,
and the world economy. Because approved drugs and vaccines are limited or not available, …

Understanding antibody-based SARS-CoV-2 immunity is critical for overcoming the COVID-19
pandemic and informing vaccination strategies. We evaluated SARS-CoV-2 antibody …

The identification and isolation of highly infectious SARS-CoV-2-infected individuals is an
important public health strategy. Rapid antigen detection tests (RADT) are promising tools for …

A fraction of COVID-19 convalescent individuals mount a potent antibody response to SARS-CoV-2
with cross-reactivity to SARS-CoV-1. To uncover their humoral response in detail, we …

The human immune response must continuously adapt to newly emerging SARS-CoV-2
variants. To investigate how B cells respond to repeated SARS-CoV-2 antigen exposure by …

Recombinant vesicular stomatitis virus–Zaire Ebola virus (rVSV-ZEBOV) is the most advanced
Ebola virus vaccine candidate and is currently being used to combat the outbreak of …

Understanding the specificities of human serum antibodies that broadly neutralize HIV can
inform prevention and treatment strategies. Here, we describe a deep mutational scanning …

HIV-1 broadly neutralizing antibodies (bNAbs) are able to suppress viremia and prevent
infection. Their induction by vaccination is therefore a major goal. However, in contrast to …