User profiles for Luv Kishore Srivastava

Luv Kishore Srivastava

Post doctoral researcher., McGill University
Verified email at mcgill.ca
Cited by 75

Spatial distribution of lamin A/C determines nuclear stiffness and stress-mediated deformation

LK Srivastava, Z Ju, A Ghagre… - Journal of cell …, 2021 - journals.biologists.com
While diverse cellular components have been identified as mechanotransduction elements,
the deformation of the nucleus itself is a critical mechanosensory mechanism, implying that …

Nuclear compression regulates YAP spatiotemporal fluctuations in living cells

N Koushki, A Ghagre, LK Srivastava… - Proceedings of the …, 2023 - National Acad Sciences
Yes-associated protein (YAP) is a key mechanotransduction protein in diverse physiological
and pathological processes; however, a ubiquitous YAP activity regulatory mechanism in …

Lamin A redistribution mediated by nuclear deformation determines dynamic localization of YAP

N Koushki, A Ghagre, LK Srivastava, C Sitaras… - BioRxiv, 2020 - biorxiv.org
YAP is a key mechanotransduction protein with essential roles in diverse physiological
processes. Dysregulation in YAP activity is associated with multiple diseases such as …

Pattern-based contractility screening, a reference-free alternative to traction force microscopy methodology

A Ghagre, A Amini, LK Srivastava, P Tirgar… - … Applied Materials & …, 2021 - ACS Publications
The sensing and generation of cellular forces are essential aspects of life. Traction force
microscopy (TFM) has emerged as a standard broadly applicable methodology to measure cell …

Nuclear stiffness regulates cellular senescence via YAP dependent mechanotransduction

LK Srivastava, A Ghagre, AJ Ehrlicher - Biophysical Journal, 2023 - cell.com
The cellular nucleus is a critical mechanosensing organelle subjected to and integrating
cytoskeletal forces for biochemical responses. Changes in nuclear stiffness influence this …

Cross-linking of Knitted Silk Scaffold for Effective Entheseal Chondrogenesis and Ligamentogenesis

LK Srivastava - 2016 - ethesis.nitrkl.ac.in
The ligament is a connective tissue that bridges two bones and stabilizes the joints during
motor activities.Anterior Cruciate Ligament(ACL)is one of the primary ligaments present in the …

[PDF][PDF] Spatial Distribution of Lamin a Determines Nuclear Stiffness and Stress-Mediated Deformation

LK Srivastava, Z Ju, A Ghagre, AJ Ehrlicher - Biophysical Journal, 2021 - cell.com
Wednesday, February 24, 2021 169a elements, the deformation of the nucleus itself is emerging
as a critical mechanosensory mechanism, suggesting that nuclear stiffness is essential …

Nuclear curvature determines Yes-Associated Protein nuclear localization and differentiation of mesenchymal stem cells

A Ghagre, A Delarue, LK Srivastava, N Koushki… - Biophysical …, 2024 - Elsevier
Controlling mesenchymal stem cells (MSCs) differentiation remains a critical challenge in their
therapeutic application. Numerous biophysical and mechanical stimuli influence stem cell …

Pattern-based Contractility Screening (PaCS), a reference-free traction force microscopy methodology, reveals contractile differences in breast cancer cells

A Ghagre, A Amini, LK Srivastava, P Tirgar, A Khavari… - bioRxiv, 2020 - biorxiv.org
The sensing and generation of cellular forces are essential aspects of life. Traction Force
Microscopy (TFM) has emerged as a standard broadly applicable methodology to measure cell …

First person–Luv Kishore Srivastava

F PERSON - 2021 - journals.biologists.com
Luv Kishore Srivastava is first author on ‘ Spatial distribution of lamin A/C determines
nuclear stiffness and stress-mediated deformation ’, published in JCS. Luv Kishore is a PhD …