During the last few years, next‐generation sequencing (NGS) technologies have
accelerated the detection of genetic variants resulting in the rapid discovery of new disease‐associated …

The antigen-specific receptor of T (ymphoc'ytes (TCR) and the Fab moiety of immunoglobulins
are expected to fold into similar threedimensional structures because of their identical pro…

PROSITE ( http://prosite.expasy.org/ ) consists of documentation entries describing protein
domains, families and functional sites, as well as associated patterns and profiles to identify …

A map of 191 single-nucleotide polymorphism (SNPs) was built across a 5-Mb segment
from chromosome 13q34 that has been genetically linked to schizophrenia. DNA from 213 …

Kallmann syndrome associates hypogonadotropic hypogonadismand anosmia and is probably
due to a defect in the embryonic migration of olfactory and GnRH-synthesizing neurons. …

The Universal Protein Resource (UniProt, http://www.uniprot.org ) consortium is an initiative
of the SIB Swiss Institute of Bioinformatics (SIB), the European Bioinformatics Institute (EBI) …

The large (L) protein subunit of unsegmented negative-strand RNA virus polymerases is
thought to be responsible for the majority of enzymic activities involved in viral transcription and …

The molecular diversity of viruses complicates the interpretation of viral genomic and proteomic
data. To make sense of viral gene functions, investigators must be familiar with the virus …

To make full use of research data, the bioscience community needs to adopt technologies
and reward mechanisms that support interoperability and promote the growth of an open 'data …

The GO annotation dataset provided by the UniProt Consortium (GOA: http://www.ebi.ac.uk/GOA
) is a comprehensive set of evidenced-based associations between terms from the …