User profiles for Lyle J. Palmer
 | Lyle John PalmerProfessor of Genetic Epidemiology, Adelaide University Verified email at adelaide.edu.au Cited by 75306 |
Population stratification and spurious allelic association
Great efforts and expense have been expended in attempts to detect genetic polymorphisms
contributing to susceptibility to complex human disease. Concomitantly, technology for …
contributing to susceptibility to complex human disease. Concomitantly, technology for …
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment
A genome-wide association study (GWAS) of educational attainment was conducted in a
discovery sample of 101,069 individuals and a replication sample of 25,490. Three …
discovery sample of 101,069 individuals and a replication sample of 25,490. Three …
Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction
Eosinophils are pleiotropic multifunctional leukocytes involved in initiation and propagation
of inflammatory responses and thus have important roles in the pathogenesis of …
of inflammatory responses and thus have important roles in the pathogenesis of …
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance
Recent genome-wide association studies have described many loci implicated in type 2
diabetes (T2D) pathophysiology and β-cell dysfunction but have contributed little to the …
diabetes (T2D) pathophysiology and β-cell dysfunction but have contributed little to the …
[HTML][HTML] AI recognition of patient race in medical imaging: a modelling study
Background Previous studies in medical imaging have shown disparate abilities of artificial
intelligence (AI) to detect a person's race, yet there is no known correlation for race on …
intelligence (AI) to detect a person's race, yet there is no known correlation for race on …
[PDF][PDF] Genomewide scans of complex human diseases: true linkage is hard to find
J Altmüller, LJ Palmer, G Fischer, H Scherb… - The American Journal of …, 2001 - cell.com
Many "complex" human diseases, which involve multiple genetic and environmental determinants,
have increased in incidence during the past 2 decades. During the same time period, …
have increased in incidence during the past 2 decades. During the same time period, …
Genome-wide association study identifies five loci associated with lung function
Pulmonary function measures are heritable traits that predict morbidity and mortality and
define chronic obstructive pulmonary disease (COPD). We tested genome-wide association …
define chronic obstructive pulmonary disease (COPD). We tested genome-wide association …
Common genetic variants of the FADS1 FADS2 gene cluster and their reconstructed haplotypes are associated with the fatty acid composition in phospholipids
Fatty acid composition in membranes plays an important role in cellular processes and has
shown to be associated with the aetiology of several complex diseases in humans. We report …
shown to be associated with the aetiology of several complex diseases in humans. We report …
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies
…, K Northstone, BA Oostra, M Peacock, LJ Palmer… - Nature …, 2010 - nature.com
To identify loci for age at menarche, we performed a meta-analysis of 32 genome-wide
association studies in 87,802 women of European descent, with replication in up to 14,731 …
association studies in 87,802 women of European descent, with replication in up to 14,731 …
Neighborhood greenspace and health in a large urban center
Many have the intuition that living near trees and greenspace is beneficial to our health. But
how much could a tree in the street or a nearby neighborhood park improve our health? …
how much could a tree in the street or a nearby neighborhood park improve our health? …