The Psychiatric Genomics Consortium-Posttraumatic Stress Disorder group (PGC-PTSD)
combined genome-wide case–control molecular genetic data across 11 multiethnic studies to …

The risk of posttraumatic stress disorder (PTSD) following trauma is heritable, but robust
common variants have yet to be identified. In a multi-ethnic cohort including over 30,000 PTSD …

The lack of reliable measures of alcohol intake is a major obstacle to the diagnosis and
treatment of alcohol-related diseases. Epigenetic modifications such as DNA methylation may …

Background Individual genotypes at specific loci can result in different patterns of DNA
methylation. These methylation quantitative trait loci (meQTLs) influence methylation across …

DNA methylation is an important epigenetic mechanism that has been linked to complex
diseases and is of great interest to researchers as a potential link between genome, …

Objective: Increased systemic inflammation is associated with stress-related psychopathology.
Specifically, levels of the proinflammatory marker C-reactive protein (CRP) are elevated …

Childhood abuse can alter biological systems and increase risk for adult psychopathology.
Epigenetic mechanisms, alterations in DNA structure that regulate the gene expression, are a …

Identifying methylation quantitative trait loci (meQTLs) and integrating them with disease-associated
variants from genome-wide association studies (GWAS) may illuminate functional …

Post-traumatic stress disorder (PTSD) is increasingly recognized as both a disorder of
enormous mental health and societal burden, but also as an anxiety disorder that may be …

Cigarette smoking is an environmental risk factor for many chronic diseases, and disease
risk can often be managed by smoking control. Smoking can induce cellular and molecular …