User profiles for Lynn M. Hartweck

Lynn Hartweck

Verified email at umn.edu
Cited by 1922

Two O-Linked N-Acetylglucosamine Transferase Genes of Arabidopsis thaliana L. Heynh. Have Overlapping Functions Necessary for Gamete and Seed …

LM Hartweck, CL Scott, NE Olszewski - Genetics, 2002 - academic.oup.com
The Arabidopsis SECRET AGENT (SEC) and SPINDLY (SPY) proteins are similar to animal
O-linked N-acetylglucosamine transferases (OGTs). OGTs catalyze the transfer of N-…

O-GlcNAc protein modification in plants: evolution and function

…, CM West, SO Sassi, LM Hartweck - Biochimica et Biophysica …, 2010 - Elsevier
The role in plants of posttranslational modification of proteins with O-linked N-acetylglucosamine
and the evolution and function of O-GlcNAc transferases responsible for this …

O-GlcNAcylation of master growth repressor DELLA by SECRET AGENT modulates multiple signaling pathways in Arabidopsis

…, B Barnhill, H Oldenhof, LM Hartweck… - Genes & …, 2016 - genesdev.cshlp.org
The DELLA family of transcription regulators functions as master growth repressors in plants
by inhibiting phytohormone gibberellin (GA) signaling in response to developmental and …

[HTML][HTML] Muscle pathology from stochastic low level DUX4 expression in an FSHD mouse model

…, SSK Chan, OO Recht, LM Hartweck… - Nature …, 2017 - nature.com
Facioscapulohumeral muscular dystrophy is a slowly progressive but devastating myopathy
caused by loss of repression of the transcription factor DUX4; however, DUX4 expression is …

Gibberellin signaling

LM Hartweck - Planta, 2008 - Springer
This review covers recent advances in gibberellin (GA) signaling. GA signaling is now
understood to hinge on DELLA proteins. DELLAs negatively regulate GA response by activating …

A focal domain of extreme demethylation within D4Z4 in FSHD2

LM Hartweck, LJ Anderson, RJ Lemmers, A Dandapat… - Neurology, 2013 - AAN Enterprises
Objective: Facioscapulohumeral muscular dystrophy (FSHD) is a neuromuscular disease
with an unclear genetic mechanism. Most patients have a contraction of the D4Z4 …

[HTML][HTML] Dominant lethal pathologies in male mice engineered to contain an X-linked DUX4 transgene

A Dandapat, D Bosnakovski, LM Hartweck, RW Arpke… - Cell reports, 2014 - cell.com
Facioscapulohumeral muscular dystrophy (FSHD) is an enigmatic disease associated with
epigenetic alterations in the subtelomeric heterochromatin of the D4Z4 macrosatellite repeat. …

The DUX4 homeodomains mediate inhibition of myogenesis and are functionally exchangeable with the Pax7 homeodomain

D Bosnakovski, EA Toso, LM Hartweck… - Journal of cell …, 2017 - journals.biologists.com
Facioscapulohumeral muscular dystrophy (FSHD) is caused by inappropriate expression of
the double homeodomain protein DUX4. DUX4 has bimodal effects, inhibiting myogenic …

Rice GIBBERELLIN INSENSITIVE DWARF1 is a gibberellin receptor that illuminates and raises questions about GA signaling

LM Hartweck, NE Olszewski - The Plant Cell, 2006 - academic.oup.com
Recently, gibberellins (GAs) joined the list of plant hormones with a known receptor protein
with the report by Ueguchi-Tanaka et al.(2005) that the GIBBERELLIN INSENSITIVE …

SECRET AGENT and SPINDLY have overlapping roles in the development of Arabidopsis thaliana L. Heyn.

LM Hartweck, RK Genger, WM Grey… - Journal of …, 2006 - academic.oup.com
O-GlcNAc transferase (OGT) catalyses transfer of GlcNAc (N-acetylglucosamine) to serine
or threonine of proteins. The Arabidopsis OGTs, SECRET AGENT (SEC) and SPINDLY (SPY) …