User profiles for M Block

Michelle L. Block

Indiana University School of Medicine, Department of Anatomy & Cell Biology. The Stark …
Verified email at iupui.edu
Cited by 20867

A psychometric toolbox for testing validity and reliability

HA DeVon, ME Block, P Moyle‐Wright… - Journal of Nursing …, 2007 - Wiley Online Library
Purpose: To review the concepts of reliability and validity, provide examples of how the
concepts have been used in nursing research, provide guidance for improving the psychometric …

Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

ML Block, L Zecca, JS Hong - Nature Reviews Neuroscience, 2007 - nature.com
Mounting evidence indicates that microglial activation contributes to neuronal damage in
neurodegenerative diseases. Recent studies show that in response to certain environmental …

Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism

ML Block, JS Hong - Progress in neurobiology, 2005 - Elsevier
Inflammation, a common denominator among the diverse list of neurodegenerative diseases,
has recently been implicated as a critical mechanism responsible for the progressive …

Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration

L Qin, X Wu, ML Block, Y Liu, GR Breese, JS Hong… - Glia, 2007 - Wiley Online Library
… toxin or neuronal death) the microglial pro-inflammatory response to neuron damage can
drive the progressive inflammation and cumulative loss of neurons over time (Block and Hong, …

Aggregated α‐synuclein activates microglia: a process leading to disease progression in Parkinson's disease

…, T Wang, Z Pei, DS Miller, X Wu, ML Block… - The FASEB …, 2005 - Wiley Online Library
… of mazindol (10 M) and NO711 (10 M) with -alanine (1 mM), respectively, was subtracted. …
of 20 M. 100 L/well of DCFH-DA, diluted to a final concentration of 40 M in phenol red-free …

Air pollution: mechanisms of neuroinflammation and CNS disease

ML Block, L Calderón-Garcidueñas - Trends in neurosciences, 2009 - cell.com
Air pollution has been implicated as a chronic source of neuroinflammation and reactive
oxygen species (ROS) that produce neuropathology and central nervous system (CNS) disease…

The motion of bubbles in a vertical temperature gradient

NO Young, JS Goldstein, MJ Block - Journal of Fluid Mechanics, 1959 - cambridge.org
… into copper blocks borne by the anvils. The temperature of the lower block could be raised
by increasing the current through a nichrome wire wrapped around the lower copper block. …

Long-term clinical effect of hemodynamically optimized cardiac resynchronization therapy in patients with heart failure and ventricular conduction delay

A Auricchio, C Stellbrink, S Sack, M Block, J Vogt… - Journal of the American …, 2002 - jacc.org
… The 6-min walk distance increased from 342 m at baseline to 386 m after the first treatment
(p < 0.001) and to 416 m after the second treatment (p = 0.03). All improvements persisted …

Microglial activation and chronic neurodegeneration

ME Lull, ML Block - Neurotherapeutics, 2010 - Elsevier
Microglia, the resident innate immune cells in the brain, have long been implicated in the
pathology of neurodegenerative diseases. Accumulating evidence points to activated microglia …

Effect of pacing chamber and atrioventricular delay on acute systolic function of paced patients with congestive heart failure

A Auricchio, C Stellbrink, M Block, S Sack, J Vogt… - Circulation, 1999 - Am Heart Assoc
block, or more severe AV conduction blocks. A limitation of our protocol is that the paced-beat
number has a significant effect on the hemodynamic response. The first beat in a pacing …