User profiles for M Kalofonou

Melpomeni Kalofonou

Research Fellow in Cancer Technology, Centre for Bio-Inspired Technology, Imperial …
Verified email at imperial.ac.uk
Cited by 593

The Fire Within: NF-κB Involvement in Non–Small Cell Lung Cancer

FID Dimitrakopoulos, AE Kottorou, M Kalofonou… - Cancer research, 2020 - AACR
Thirty-four years since its discovery, NF-κB remains a transcription factor with great potential
for cancer therapy. However, NF-κB–targeted therapies have yet to find a way to be …

[HTML][HTML] The Evolution of Affordable Technologies in Liquid Biopsy Diagnostics: The Key to Clinical Implementation

…, RC Coombes, C Toumazou, JA Shaw, M Kalofonou - Cancers, 2023 - mdpi.com
Simple Summary This review aims to highlight the usage of circulating tumour DNA and
circulating tumour cells in various manners for the care of cancer patients. The different …

Detection of Multiple Breast Cancer ESR1 Mutations on an ISFET Based Lab-on-Chip Platform

…, P Georgiou, C Toumazou, M Kalofonou - IEEE transactions on …, 2021 - ieeexplore.ieee.org
… [29] M. Kalofonou et al., “A novel hotspot specific isothermal amplification method for
detection of the common PIK3CA p.H1047R breast cancer mutation,” Sci. Rep., vol. …

[HTML][HTML] A novel hotspot specific isothermal amplification method for detection of the common PIK3CA p.H1047R breast cancer mutation

M Kalofonou, K Malpartida-Cardenas, G Alexandrou… - Scientific reports, 2020 - nature.com
Breast cancer (BC) is a common cancer in women worldwide. Despite advances in treatment,
up to 30% of women eventually relapse and die of metastatic breast cancer. Liquid biopsy …

Adapting ISFETs for epigenetics: An overview

…, S de Mateo Lopez, M Kalofonou… - IEEE transactions on …, 2018 - ieeexplore.ieee.org
This paper gives an overview of how CMOS design methods can be applied to ion-sensitive
field effect transistor (ISFETs) for pH-based DNA methylation and miRNA detection. Design …

[HTML][HTML] Lab-on-chip assay of tumour markers and human papilloma virus for cervical cancer detection at the point-of-care

…, I Pennisi, TEJ Ind, K Vroobel, M Kalofonou… - Scientific Reports, 2022 - nature.com
Cervical cancer affects over half a million people worldwide each year, the majority of whom
are in resource-limited settings where cytology screening is not available. As persistent …

Semiconductor technology for early detection of DNA methylation for cancer: From concept to practice

M Kalofonou, C Toumazou - Sensors and Actuators B: Chemical, 2013 - Elsevier
… In this study, the methylated state of the genes (DAPK1 M and p16 M ) was defined as all
methylated cytosines remaining unaltered after bisulfite treatment while unmethylated cytosines …

A Low Power Sub-W Chemical Gilbert Cell for ISFET Differential Reaction Monitoring

M Kalofonou, C Toumazou - IEEE transactions on biomedical …, 2013 - ieeexplore.ieee.org
… area of 34 m 100 m. All sizes of PMOS devices used were optimised at (W/L) 10 m/10 m so
that … The area covered by circuit was 1960 m (70 m 28 m). Furthermore, both ISFETs were …

[HTML][HTML] Expression of intracellular components of the NF-κB alternative pathway (NF-κB2, RelB, NIK and Bcl3) is associated with clinical outcome of NSCLC patients

…, F Kalofonou, F Sampsonas, C Scopa, M Kalofonou… - Scientific reports, 2019 - nature.com
A growing number of studies has shed light on the role of the NF-κΒ in non-small-cell lung
cancer (NSCLC). To address the significance of major effectors of the NF-κΒ alternative …

Study of the historical mortars of the Holy Aedicule as a basis for the design, application and assessment of repair mortars: A multispectral approach applied on the …

…, ET Delegou, E Alexakis, M Kalofonou… - … and Building Materials, 2018 - Elsevier
The rehabilitation of the Holy Aedicule of the Holy Sepulchre in Jerusalem, completed in
March 2017, aimed to address the deformation problems encountered after its most recent …