Cardiovascular diseases (CVDs) are pointed out by the World Health Organization (WHO)
as the leading cause of death, contributing to a significant and growing global health and …

The LTα 1 β 2 and LIGHT TNF superfamily cytokines exert pleiotropic physiological functions
through the activation of their cognate lymphotoxin-β receptor (LTβR). Interestingly, since …

CITED2 (CBP/p300-interacting transactivator with Glu/Asp-rich C-terminal domain, 2) is a
ubiquitously expressed protein exhibiting a high affinity for the CH1 domain of the …

Lymphotoxin‐mediated activation of the lymphotoxin‐β receptor (LTβR; LTBR) has been
implicated in cancer, but its role in T‐cell acute lymphoblastic leukaemia (T‐ALL) has remained …

Two main NF-κB signaling pathways, canonical and noncanonical, performing distinct
functions in organisms have been characterized. Identification of mutations in genes encoding …

T-cell acute lymphoblastic leukemia (T-ALL) and T-lymphoblastic lymphomas (T-LBL) are
aggressive malignancies of thymocytes. The role of thymic microenvironmental cells and …

Congenital heart diseases (CHDs) are structural or functional defects present at birth due to
improper heart development. Current therapeutic approaches to treating severe CHDs are …

Peritoneal protein loss (PPL) has been correlated with mortality, malnutrition and inflammation.
More recently overhydration was brought to the equation. This study aims to review …

CDKN2A deletion is the most frequent genetic alteration in T-cell acute lymphoblastic
leukemia (T-ALL), occurring across all molecular and immunophenotypic subtypes. CDKN2A …

… Author links open overlay panel Mónica T. Fernandes a b c , Hélder Almeida-Lousada b c
d … and B cells, and/or impaired suppressive function of regulatory T cells. Even though the …