An illustrated review of early pancreas development in the mouse
MC Jørgensen, J Ahnfelt-Rønne, J Hald… - Endocrine …, 2007 - academic.oup.com
Pancreas morphogenesis and cell differentiation are highly conserved among vertebrates
during fetal development. The pancreas develops through simple budlike structures on the …
during fetal development. The pancreas develops through simple budlike structures on the …
Transcription factors contributing to the pancreatic β-cell phenotype
…, A Øster, FG Andersen, MC Jørgensen… - Hormone and …, 1997 - thieme-connect.com
Insulin promoter factor-1 (IPF1)(renamed to pancreaticduodenal homeobox factor-1, PDX1)
was originally cloned and characterized as an islet β-cell specific insulin gene transcription …
was originally cloned and characterized as an islet β-cell specific insulin gene transcription …
[HTML][HTML] Retinoic acid signaling organizes endodermal organ specification along the entire antero-posterior axis
E Bayha, MC Jørgensen, P Serup, A Grapin-Botton - PloS one, 2009 - journals.plos.org
Background Endoderm organ primordia become specified between gastrulation and gut
tube folding in Amniotes. Although the requirement for RA signaling for the development of a …
tube folding in Amniotes. Although the requirement for RA signaling for the development of a …
Behaviour patterns and time course of activity in dogs with separation problems
JD Lund, MC Jørgensen - Applied Animal Behaviour Science, 1999 - Elsevier
An analysis of video-recordings of 20 dogs with separation problems suggested that
separation behaviour may be divided into: (1) exploratory behaviour, (2) object play including …
separation behaviour may be divided into: (1) exploratory behaviour, (2) object play including …
B-Cell Epitopes and Quantification of the ESAT-6 Protein of Mycobacterium tuberculosis
…, G Ulvund, A Holm, MC Jørgensen… - Infection and …, 1998 - Am Soc Microbiol
ESAT-6 is an important T-cell antigen recognized by protective T cells in animal models of
infection with Mycobacterium tuberculosis. In an enzyme-linked immunosorbent assay (ELISA…
infection with Mycobacterium tuberculosis. In an enzyme-linked immunosorbent assay (ELISA…
Mind bomb 1 is required for pancreatic β-cell formation
S Horn, S Kobberup, MC Jørgensen… - Proceedings of the …, 2012 - National Acad Sciences
During early pancreatic development, Notch signaling represses differentiation of endocrine
cells and promotes proliferation of Nkx6-1 + Ptf1a + multipotent progenitor cells (MPCs). …
cells and promotes proliferation of Nkx6-1 + Ptf1a + multipotent progenitor cells (MPCs). …
An improved method for three-dimensional reconstruction of protein expression patterns in intact mouse and chicken embryos and organs
J Ahnfelt-Rønne, MC Jørgensen… - … of Histochemistry & …, 2007 - journals.sagepub.com
We have developed a wholemount immunofluorescence protocol for the simultaneous detection
of up to three proteins in mouse and chicken embryos. Combined with Murray's clearing …
of up to three proteins in mouse and chicken embryos. Combined with Murray's clearing …
Ptf1a-mediated control of Dll1 reveals an alternative to the lateral inhibition mechanism
J Ahnfelt-Rønne, MC Jørgensen, R Klinck… - …, 2012 - journals.biologists.com
Neurog3-induced Dll1 expression in pancreatic endocrine progenitors ostensibly activates
Hes1 expression via Notch and thereby represses Neurog3 and endocrine differentiation in …
Hes1 expression via Notch and thereby represses Neurog3 and endocrine differentiation in …
[PDF][PDF] Jag1 modulates an oscillatory Dll1-Notch-Hes1 signaling module to coordinate growth and fate of pancreatic progenitors
…, A la Rosa Egeskov-Madsen, MC Jørgensen… - Developmental cell, 2020 - cell.com
Notch signaling controls proliferation of multipotent pancreatic progenitor cells (MPCs) and
their segregation into bipotent progenitors (BPs) and unipotent pro-acinar cells (PACs). Here, …
their segregation into bipotent progenitors (BPs) and unipotent pro-acinar cells (PACs). Here, …
[HTML][HTML] Jag1-Notch cis-interaction determines cell fate segregation in pancreatic development
…, AR Egeskov-Madsen, MC Jørgensen… - Nature …, 2023 - nature.com
The Notch ligands Jag1 and Dll1 guide differentiation of multipotent pancreatic progenitor
cells (MPCs) into unipotent pro-acinar cells (PACs) and bipotent duct/endocrine progenitors (…
cells (MPCs) into unipotent pro-acinar cells (PACs) and bipotent duct/endocrine progenitors (…