User profiles for M. C. Whitlock
Michael WhitlockProfessor of Zoology, University of British Columbia Verified email at zoology.ubc.ca Cited by 24114 |
The incomplete natural history of mitochondria
JWO Ballard, MC Whitlock - Molecular ecology, 2004 - Wiley Online Library
Mitochondrial DNA (mtDNA) has been used to study molecular ecology and phylogeography
for 25 years. Much important information has been gained in this way, but it is time to reflect …
for 25 years. Much important information has been gained in this way, but it is time to reflect …
Assisted gene flow to facilitate local adaptation to climate change
SN Aitken, MC Whitlock - Annual review of ecology, evolution …, 2013 - annualreviews.org
Assisted gene flow (AGF) between populations has the potential to mitigate maladaptation
due to climate change. However, AGF may cause outbreeding depression (especially if …
due to climate change. However, AGF may cause outbreeding depression (especially if …
Experimental evolution
Experimental evolution is the study of evolutionary processes occurring in experimental
populations in response to conditions imposed by the experimenter. This research approach is …
populations in response to conditions imposed by the experimenter. This research approach is …
Indirect measures of gene flow and migration: FST≠1/(4Nm+1)
MC Whitlock, DE McCauley - Heredity, 1999 - Wiley Online Library
… WHITLOCK, MC1992a. Nonequilibrium population structure in forked fungus beetles: …
WHITLOCK, MC1992b. Temporal fluctuations in demographic parameters and the genetic …
WHITLOCK, MC1992b. Temporal fluctuations in demographic parameters and the genetic …
Fixation probability and time in subdivided populations
MC Whitlock - Genetics, 2003 - academic.oup.com
New alleles arising in a population by mutation ultimately are either fixed or lost. Either is
possible, for both beneficial and deleterious alleles, because of stochastic changes in allele …
possible, for both beneficial and deleterious alleles, because of stochastic changes in allele …
Combining probability from independent tests: the weighted Z‐method is superior to Fisher's approach
MC Whitlock - Journal of evolutionary biology, 2005 - academic.oup.com
The most commonly used method in evolutionary biology for combining information across
multiple tests of the same null hypothesis is Fisher's combined probability test. This note …
multiple tests of the same null hypothesis is Fisher's combined probability test. This note …
Perspective: evolution and detection of genetic robustness
Robustness is the invariance of phenotypes in the face of perturbation. The robustness of
phenotypes appears at various levels of biological organization, including gene expression, …
phenotypes appears at various levels of biological organization, including gene expression, …
Finding the genomic basis of local adaptation: pitfalls, practical solutions, and future directions
… allele surfing (Lotterhos and Whitlock 2014, 2015) and none have included background
selection. … Aitken, SN, and MC Whitlock. 2013. Assisted gene flow to facilitate local adaptation to …
selection. … Aitken, SN, and MC Whitlock. 2013. Assisted gene flow to facilitate local adaptation to …
The genetic architecture of adaptation under migration–selection balance
S Yeaman, MC Whitlock - Evolution, 2011 - academic.oup.com
Many ecologically important traits have a complex genetic basis, with the potential for mutations
at many different genes to shape the phenotype. Even so, studies of local adaptation in …
at many different genes to shape the phenotype. Even so, studies of local adaptation in …
Evaluation of demographic history and neutral parameterization on the performance of FST outlier tests
KE Lotterhos, MC Whitlock - Molecular ecology, 2014 - Wiley Online Library
F ST outlier tests are a potentially powerful way to detect genetic loci under spatially divergent
selection. Unfortunately, the extent to which these tests are robust to nonequilibrium …
selection. Unfortunately, the extent to which these tests are robust to nonequilibrium …