Several gene mutations responsible for human cancer initiation have been discovered, whereas
only a few have been identified in association with the progression to metastasis. In this …

The MET oncogene was causally involved in the pathogenesis of a rare tumor, ie, the
papillary renal cell carcinoma, in which activating mutations, either germline or somatic, were …

Companion animal spontaneous tumors are suitable models for human cancer, primarily
because both animal population and the tumors are genetically heterogeneous. Feline …

Hepatocyte Growth Factor (HGF, also known as Scatter Factor) is a powerful mitogen or
motility factor in different cells, acting through the tyrosine kinase receptor encoded by the MET …

The c-met oncogene encodes the receptor for hepatocyte growth factor/scatter factor, a
potent mitogen for epithelial cells that also promotes cell motility and invasiveness. We have …

The MET oncogene encodes a transmembrane tyrosine kinase receptor. Recently, hepatocyte
growth factor (HGF), a potent growth factor for hepatocytes involved in liver regeneration, …

… MF Di Renzo … et al., 1995b), and is amplified in liver metastases of colorectal carcinomas
(Di Renzo et al., 1995a). Germline missense mutations in the tyrosine kinase … MF Di Renzo …

RON is a tyrosine kinase receptor that triggers scattering of normal cells and invasive growth
of cancer cells on ligand binding. We identified a short RON mRNA, which is expressed in …

The c-MET oncogene encodes the receptor for the Hepatocyte Growth Factor/Scatter Factor
(HGF), a cytokine that stimulates the invasive growth of normal and neoplastic cells. The Met/…

The c-MET oncogene encodes the receptor for hepatocyte growth factor (HGF) scatter factor,
a multifunctional cytokine able to mediate morphogenesis as well as invasive growth of …