Ancient DNA studies in physical anthropology

DH O'Rourke, MG Hayes… - Annual Review of …, 2000 - annualreviews.org
▪ Abstract Nucleic acids are preserved in prehistoric samples under a wide range of depositional
environments. The development of new molecular methods, especially the polymerase …

Arthroscopic treatment of adhesive capsulitis

…, DE Taylor, CS Hogan, AD Saies, MG Hayes - Journal of shoulder and …, 1995 - Elsevier
Although conservative management with or without manipulation performed with the patient
under anesthesia is the generally accepted treatment strategy for adhesive capsulitis, …

Genetics of gestational diabetes mellitus and maternal metabolism

WL Lowe, DM Scholtens, V Sandler, MG Hayes - Current diabetes reports, 2016 - Springer
Gestational diabetes mellitus (GDM) is defined as abnormal glucose tolerance with onset or
first recognition during pregnancy. Women with a history of GDM are at long-term risk for …

[HTML][HTML] Microbiome differential abundance methods produce different results across 38 datasets

JT Nearing, GM Douglas, MG Hayes… - Nature …, 2022 - nature.com
Identifying differentially abundant microbes is a common goal of microbiome studies. Multiple
methods are used interchangeably for this purpose in the literature. Yet, there are few large…

Genome partitioning of genetic variation for complex traits using common SNPs

…, M De Andrade, B Feenstra, E Feingold, MG Hayes… - Nature …, 2011 - nature.com
We estimate and partition genetic variation for height, body mass index (BMI), von
Willebrand factor and QT interval (QTi) using 586,898 SNPs genotyped on 11,586 unrelated …

Insulin gene mutations as a cause of permanent neonatal diabetes

…, A Pluzhnikov, JE Below, MG Hayes… - Proceedings of the …, 2007 - National Acad Sciences
We report 10 heterozygous mutations in the human insulin gene in 16 probands with neonatal
diabetes. A combination of linkage and a candidate gene approach in a family with four …

Detectable clonal mosaicism from birth to old age and its relationship to cancer

…, SM Armasu, C Regnier, WL Lowe, MG Hayes… - Nature …, 2012 - nature.com
We detected clonal mosaicism for large chromosomal anomalies (duplications, deletions
and uniparental disomy) using SNP microarray data from over 50,000 subjects recruited for …

[HTML][HTML] Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria

…, R Saxena, T Laisk, M Urbanek, MG Hayes… - PLoS …, 2018 - journals.plos.org
Polycystic ovary syndrome (PCOS) is a disorder characterized by hyperandrogenism,
ovulatory dysfunction and polycystic ovarian morphology. Affected women frequently have …

The genetic prehistory of the New World Arctic

…, K Dneprovsky, C Andreasen, H Lange, MG Hayes… - Science, 2014 - science.org
I ntroduction Humans first peopled the North American Arctic (northern Alaska, Canada, and
Greenland) around 6000 years ago, leaving behind a complex archaeological record that …

[HTML][HTML] Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations

MG Hayes, M Urbanek, DA Ehrmann… - Nature …, 2015 - nature.com
Polycystic ovary syndrome (PCOS) is a common, highly heritable complex disorder of
unknown aetiology characterized by hyperandrogenism, chronic anovulation and defects in …