Animal transcriptomes are dynamic, with each cell type, tissue and organ system expressing
an ensemble of transcript isoforms that give rise to substantial diversity. Here we have …

The transcriptome is the readout of the genome. Identifying common features in it across distant
species can reveal fundamental principles. To this end, the ENCODE and modENCODE …

Fasting glucose and insulin are intermediate traits for type 2 diabetes. Here we explore the
role of coding variation on these traits by analysis of variants on the HumanExome BeadChip …

The identification of full length transcripts entirely from short-read RNA sequencing data (RNA-seq)
remains a challenge in the annotation of genomes. Here we describe an automated …

Natural habitats are exposed to an increasing number of environmental stressors that cause
important ecological consequences. However, the multifarious nature of environmental …

Luminal epithelial cells in the breast gradually alter gene and protein expression with age,
appearing to lose lineage-specificity by acquiring myoepithelial-like characteristics. We …

In eukaryotic cells, RNAs exist as ribonucleoprotein particles (RNPs). Despite the importance
of these complexes in many biological processes, including splicing, polyadenylation, …

Background Over the past few years the variety of experimental designs and protocols for
sequencing experiments increased greatly. To ensure the wide usability of the produced data …

Background: Over the past few years the variety of experimental designs and protocols for
sequencing experiments increased greatly. To ensure the wide usability of the produced data …

Electrospinning is an advanced and versatile additive manufacturing method for the
fabrication of small-diameter, nanofibrous scaffolds. However, because of various instabilities, …