Zebrafish larvae as a model system for systematic characterization of drugs and genes in dyslipidemia and atherosclerosis
MK Bandaru, A Emmanouilidou, P Ranefall… - bioRxiv, 2018 - biorxiv.org
Hundreds of loci have been robustly associated with circulating lipids, atherosclerosis and
coronary artery disease; but for most loci the causal genes and mechanisms remain …
coronary artery disease; but for most loci the causal genes and mechanisms remain …
Zebrafish larvae as a model system for high-throughput screens of early-stage atherosclerosis
MK Bandaru, P Ranefall, A Emmanouilidou, L Tao… - Circulation, 2015 - Am Heart Assoc
Introduction: A high-cholesterol diet has been reported to induce vascular deposition of lipids
and oxidized LDL cholesterol in macrophages and other cell types in 15 day-old zebrafish …
and oxidized LDL cholesterol in macrophages and other cell types in 15 day-old zebrafish …
[HTML][HTML] Zebrafish models for large-scale genetic screens in dyslipidemia and atherosclerosis: Validation and application
MK Bandaru - 2019 - diva-portal.org
In Study III, I examined the effects of mutations in pcsk9 on atherosclerosis and diabetesrelated
traits in nearly 5,000 zebrafish larvae. Similar to the loss-of-function mutations in PCSK9 …
traits in nearly 5,000 zebrafish larvae. Similar to the loss-of-function mutations in PCSK9 …
[HTML][HTML] Apoc2 mutant zebrafish: a model for hypertriglyceridemia and early-stage atherosclerosis
MK Bandaru, A Emmanouilidou, A Larsson, I Erik… - 2019 - diva-portal.org
Zebrafish larvae in a hypertriglyceridemic background can be useful to identify and characterize
causal genes for triglyceride metabolism. A previous, small-scale study suggested that …
causal genes for triglyceride metabolism. A previous, small-scale study suggested that …
[HTML][HTML] Image-based, in vivo characterization of cardiometabolic consequences of mutations in pcsk9
MK Bandaru, E Mazzaferro, A Emmanouilidou… - 2019 - diva-portal.org
Based on the association of loss-of-function mutations in proprotein convertase subtilisin/kexin
type 9 (PCSK9) with low plasma LDL cholesterol levels, inhibition of the PCSK9 protein …
type 9 (PCSK9) with low plasma LDL cholesterol levels, inhibition of the PCSK9 protein …
Zebrafish Larvae: A Model System for Early Stage Atherosclerosis?
MK Bandaru, P Ranefall, A Emmanouilidou… - … and Vascular Biology, 2015 - Am Heart Assoc
Objectives: Published results show that overfeeding zebrafish larvae on a high-cholesterol
diet (HCD) can result in hypercholesterolemia and sub-endothelial lipid deposition in …
diet (HCD) can result in hypercholesterolemia and sub-endothelial lipid deposition in …
[HTML][HTML] Elitable GE-filters of bordered GE-algebras
In this paper, the notions of maximal GE-filter and prime GE-filter of a GE-algebra are introduced
and the relation between them is given. Some characterizations of prime GE-filters of a …
and the relation between them is given. Some characterizations of prime GE-filters of a …
GE-Morphisms of GE-Algebras.
In this paper, the notion of GE-morphism is introduced, and established fundamental GE-morphism
theorem. We investigated some isomorphism theorems in GE-algebras. We derived …
theorem. We investigated some isomorphism theorems in GE-algebras. We derived …
[PDF][PDF] Extended GE-filters in weak eGE-algebras
… As a generalization of Hilbert algebras, RK Bandaru et al.[1] introduced the notion of GE-algebras.
They studied the various properties and filter theory of GE-algebras [2, 11, 15]…
They studied the various properties and filter theory of GE-algebras [2, 11, 15]…
[PDF][PDF] On GE-ideals of bordered GE-algebras
In this paper, the properties of GE-ideals of transitive bordered GE-algebra are studied and
characterizations of GE-ideals are given. We have observed that the set of all GE-ideals of a …
characterizations of GE-ideals are given. We have observed that the set of all GE-ideals of a …