User profiles for M. K. Jolly

Mohit Kumar Jolly

Associate Professor, Indian Institute of Science, Bangalore
Verified email at iisc.ac.in
Cited by 10800

[HTML][HTML] Implications of the hybrid epithelial/mesenchymal phenotype in metastasis

MK Jolly, M Boareto, B Huang, D Jia, M Lu… - Frontiers in …, 2015 - frontiersin.org
Transitions between epithelial and mesenchymal phenotypes – the epithelial to mesenchymal
transition (EMT) and its reverse the mesenchymal to epithelial transition (MET) – are …

[HTML][HTML] Withdrawal of digoxin from patients with chronic heart failure treated with angiotensin-converting-enzyme inhibitors

…, L Van Voorhees, LA Gourley, MK Jolly - … England Journal of …, 1993 - Mass Medical Soc
Background Although digoxin is effective in the treatment of patients with chronic heart failure
who are receiving diuretic agents, it is not clear whether the drug has a role when patients …

[HTML][HTML] Tumor budding: the name is EMT. Partial EMT.

AD Grigore, MK Jolly, D Jia, MC Farach-Carson… - Journal of clinical …, 2016 - mdpi.com
Tumor budding is a histological phenomenon encountered in various cancers, whereby
individual malignant cells and/or small clusters of malignant cells are seen in the tumor stroma. …

EMT and MET: necessary or permissive for metastasis?

MK Jolly, KE Ware, S Gilja, JA Somarelli… - Molecular …, 2017 - Wiley Online Library
Epithelial‐to‐mesenchymal transition ( EMT ) and its reverse mesenchymal‐to‐epithelial
transition ( MET ) have been suggested to play crucial roles in metastatic dissemination of …

Hybrid epithelial/mesenchymal phenotypes promote metastasis and therapy resistance across carcinomas

MK Jolly, JA Somarelli, M Sheth, A Biddle… - Pharmacology & …, 2019 - Elsevier
Cancer metastasis and therapy resistance are the major unsolved clinical challenges, and
account for nearly all cancer-related deaths. Both metastasis and therapy resistance are …

Decoding leader cells in collective cancer invasion

…, F Bocci, H Levine, JN Onuchic, MK Jolly… - Nature Reviews …, 2021 - nature.com
Collective cancer invasion with leader–follower organization is increasingly recognized as
a predominant mechanism in the metastatic cascade. Leader cells support cancer invasion …

Randomized study assessing the effect of digoxin withdrawal in patients with mild to moderate chronic congestive heart failure: results of the PROVED trial

…, FE Shahidi, LG Yellen, MC Harrison, MK Jolly… - Journal of the American …, 1993 - Elsevier
Objectives. The purpose of this study was to determine whether digoxin is effective in
patients with chronic, stable mild to moderate heart failure. Background. Digoxin has been a …

MicroRNA-based regulation of epithelial–hybrid–mesenchymal fate determination

M Lu, MK Jolly, H Levine… - Proceedings of the …, 2013 - National Acad Sciences
Forward and backward transitions between epithelial and mesenchymal phenotypes play
crucial roles in embryonic development and tissue repair. Aberrantly regulated transitions are …

[HTML][HTML] Stability of the hybrid epithelial/mesenchymal phenotype

MK Jolly, SC Tripathi, D Jia, SM Mooney, M Celiktas… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Epithelial-to-Mesenchymal Transition (EMT) and its reverse–Mesenchymal to Epithelial
Transition (MET)–are hallmarks of cellular plasticity during embryonic development and cancer …

Identification of EMT signaling cross-talk and gene regulatory networks by single-cell RNA sequencing

…, R Soundararajan, MK Jolly… - Proceedings of the …, 2021 - National Acad Sciences
The epithelial-to-mesenchymal transition (EMT) plays a critical role during normal development
and in cancer progression. EMT is induced by various signaling pathways, including TGF…