… MgCl 2 and 2 mM DTT) in the presence or absence of 2 mM ATP, and complexes were
analyzed on Bis-Tris NativePAGE (Life Technologies). Fluorescent gel images were recorded …

Status epilepticus (SE) is one of the most common neurological emergencies in children. To
date, there is no definitive evidence to guide treatment of SE refractory to benzodiazepines. …

Sequencing-based studies have identified novel risk genes associated with severe epilepsies
and revealed an excess of rare deleterious variation in less-severe forms of epilepsy. To …

Objective: To evaluate the phenotypic spectrum associated with mutations in TBC1D24.
Methods: We acquired new clinical, EEG, and neuroimaging data of 11 previously unreported …

Introduction While monophasic and relapsing forms of myelin oligodendrocyte glycoprotein
antibody associated disorders (MOGAD) are increasingly diagnosed world-wide, consensus …

Contactin-associated protein-like 2 (CNTNAP2) gene encodes for CASPR2, a presynaptic
type 1 transmembrane protein, involved in cell–cell adhesion and synaptic interactions. …

Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels control neuronal
excitability and their dysfunction has been linked to epileptogenesis but few individuals with …

Objective: To conduct an open-label, add-on trial on safety and efficacy of levetiracetam in
severe myoclonic epilepsy of infancy (SMEI). Patients and Methods: SMEI patients were …

… This allows the formation of a transition zone of approximately 1 mm between the ablation
zone and normal brain tissue, which is monitored in near real time by MR thermometry (6, 7). …

… MgCl 2 , 5 mM EDTA, 1 mM dithiothreitol, 20-fold excess of mant GDP] and subsequently
adding 10 mM MgCl 2 (final concentration) to stop the reaction. Remaining non-bound …