Multicellular organisms evolved to resolve conflicts between individual cells, protecting the
internal organization of the individual. This is illustrated by cell competition, a process that …

Viable yet damaged cells can accumulate during development and aging. Although
eliminating those cells may benefit organ function, identification of this less fit cell population …

Low and middle-income countries have a greater risk of living in poverty, being exposed to
violence, and being serviced by precarious health systems. The COVID-19 pandemic and …

Background The flower gene has been previously linked to the elimination of slow dividing
epithelial cells during development in a process known as "cell competition." During cell …

The transforming growth factor-β (TGF-β)-type morphogens are conserved throughout the
animal kingdom. TGF-β-type molecules form spatial concentration gradients whose length …

… Scale bar: 10 mm in color pictures or 5 mm in grayscale insets. (D) Mean number of vacuoles
located at a 10-mmdeep plan in 2-week-old brains of the indicated genotypes. Data are …

During development, morphogen gradients encode positional information to pattern
morphological structures during organogenesis 1 . Some gradients, like that of Dpp in the fly wing, …

Cell Competition emerged in Drosophila as an unexpected phenomenon, when confronted
clones of fit vs unfit cells genetically induced. During the last decade, it has been shown that …

The earliest metazoans probably evolved from single-celled organisms which found the
colonial system to be a beneficial organization. Over the course of their evolution, these primary …

… All pathologic material was reviewed by a senior pathologist (MM) for the presence of
neighboring in situ lesions, eosinophilia, vascular invasion, histologic grade, nodal metastases, …