User profiles for M. M. Mhlanga

musa m. mhlanga

Professor, Radboud Institute for Molecular Life Sciences,
Verified email at mhlangalab.org
Cited by 9167

[HTML][HTML] Defining trained immunity and its role in health and disease

…, JWM van der Meer, MM Mhlanga… - Nature Reviews …, 2020 - nature.com
Immune memory is a defining feature of the acquired immune system, but activation of the
innate immune system can also result in enhanced responsiveness to subsequent triggers. …

[PDF][PDF] The intersection of epigenetics and metabolism in trained immunity

…, LAB Joosten, MG Netea, MM Mhlanga - Immunity, 2021 - cell.com
The last few years have witnessed an increasing body of evidence that challenges the
traditional view that immunological memory is an exclusive trait of the adaptive immune system. …

PALM and STORM: unlocking live‐cell super‐resolution

…, C Griffiths, E Hesper Rego, MM Mhlanga - …, 2011 - Wiley Online Library
Live‐cell fluorescence light microscopy has emerged as an important tool in the study of
cellular biology. The development of fluorescent markers in parallel with super‐resolution …

QuickPALM: 3D real-time photoactivation nanoscopy image processing in ImageJ

…, EF Fornasiero, F Valtorta, C Zimmer, MM Mhlanga - Nature …, 2010 - nature.com
To the Editor: Although conventional microscopes have a resolution limited by diffraction to
about half the wavelength of light, several recent advances have led to microscopy methods …

Visualizing the distribution and transport of mRNAs in living cells

DP Bratu, BJ Cha, MM Mhlanga… - Proceedings of the …, 2003 - National Acad Sciences
… -μl solution containing 40 mM Tris·HCl (pH 8.0), 10 mM MgSO 4 , 1 mM CaCl 2 , and 160 …
of a 125-μl solution containing 20 mM Tris·HCl (pH 8.0), 1 mM MgCl 2 , and 80 nM molecular …

Spectral genotyping of human alleles

LG Kostrikis, S Tyagi, MM Mhlanga, DD Ho, FR Kramer - Science, 1998 - science.org
Accelerated by the human genome project [HN1], an increasing number of genetic variations,
many as small as a single nucleotide substitution [HN2], have been found to play a …

Statin Therapy Reduces the Mycobacterium tuberculosis Burden in Human Macrophages and in Mice by Enhancing Autophagy and Phagosome Maturation

…, DM Lang, R Hurdayal, MM Mhlanga… - The Journal of …, 2014 - academic.oup.com
Background. Statins are cholesterol-lowering drugs, targeting HMG-CoA reductase, thereby
reducing the risk of coronary disorders and hypercholesterolemia. However, they also can …

[PDF][PDF] BCG vaccination induces long-term functional reprogramming of human neutrophils

…, LAB Joosten, I Joosten, H Koenen, MM Mhlanga… - Cell reports, 2020 - cell.com
… In order to remove erythrocytes, the cells were treated twice with hypotonic lysis buffer (155
mM NH4Cl, 10 mM KHCO3) during incubation on ice for 15 minutes. Next, PMNs were …

Using molecular beacons to detect single-nucleotide polymorphisms with real-time PCR

MM Mhlanga, L Malmberg - Methods, 2001 - Elsevier
… taining 200 nM of molecular beacon, 3.5 mM MgCl2, and 10 mM Tris–HCl, pH 8.0, in a
total volume of 50 μl should be prepared. Six tubes are used if doing a DNA Samples duplex …

Immune genes are primed for robust transcription by proximal long noncoding RNAs located in nuclear compartments

…, D Grimm, KC Wang, G Li, WK Sung, MM Mhlanga - Nature …, 2019 - nature.com
… de-stained using 50 mM NH 4 HCO 3 /50% MeOH followed by in-gel protein reduction (50
mM DTT in 25 mM NH 4 HCO 3 ) and alkylation (55 mM iodoacetamide in 25 mM NH 4 HCO 3 …