Persistent organic pollutants and β-cell toxicity: a comprehensive review
MP Hoyeck, G Matteo… - American Journal …, 2022 - journals.physiology.org
Persistent organic pollutants (POPs) are a diverse family of contaminants that show widespread
global dispersion and bioaccumulation. Humans are continuously exposed to POPs …
global dispersion and bioaccumulation. Humans are continuously exposed to POPs …
[HTML][HTML] Functional cytochrome P450 1A enzymes are induced in mouse and human islets following pollutant exposure
M Ibrahim, EM MacFarlane, G Matteo, MP Hoyeck… - Diabetologia, 2020 - Springer
Aims/hypothesis Exposure to environmental pollution has been consistently linked to diabetes
incidence in humans, but the potential causative mechanisms remain unclear. Given the …
incidence in humans, but the potential causative mechanisms remain unclear. Given the …
[HTML][HTML] Long-term metabolic consequences of acute dioxin exposure differ between male and female mice
MP Hoyeck, H Blair, M Ibrahim, S Solanki, M Elsawy… - Scientific reports, 2020 - nature.com
Epidemiological studies have consistently shown an association between exposure to
environmental pollutants and diabetes risk in humans. We have previously shown that direct …
environmental pollutants and diabetes risk in humans. We have previously shown that direct …
[HTML][HTML] Female mice exposed to low doses of dioxin during pregnancy and lactation have increased susceptibility to diet-induced obesity and diabetes
MP Hoyeck, RC Merhi, HL Blair, CD Spencer… - Molecular …, 2020 - Elsevier
Objective Exposure to persistent organic pollutants is consistently associated with increased
diabetes risk in humans. We investigated the short- and long-term impact of transient low-…
diabetes risk in humans. We investigated the short- and long-term impact of transient low-…
The aryl hydrocarbon receptor in β-cells mediates the effects of TCDD on glucose homeostasis in mice
MP Hoyeck, MEA Ching, L Basu, K Van Allen… - Molecular …, 2024 - Elsevier
Objective Chronic exposure to persistent organic pollutants (POPs) is associated with
increased incidence of type 2 diabetes, hyperglycemia, and poor insulin secretion in humans. …
increased incidence of type 2 diabetes, hyperglycemia, and poor insulin secretion in humans. …
Prolonged low-dose dioxin exposure impairs metabolic adaptability to high-fat diet feeding in female but not male mice
G Matteo, MP Hoyeck, HL Blair, J Zebarth… - …, 2021 - academic.oup.com
… Myriam P Hoyeck , Myriam P Hoyeck … Geronimo Matteo, Myriam P Hoyeck, Hannah L Blair,
Julia Zebarth, Kayleigh RC Rick, Andrew Williams, Rémi Gagné, Julie K Buick, Carole L Yauk…
Julia Zebarth, Kayleigh RC Rick, Andrew Williams, Rémi Gagné, Julie K Buick, Carole L Yauk…
[HTML][HTML] Estivation-responsive microRNAs in a hypometabolic terrestrial snail
MP Hoyeck, H Hadj-Moussa, KB Storey - PeerJ, 2019 - peerj.com
When faced with extreme environmental conditions, the milk snail (Otala lactea) enters a state
of dormancy known as estivation. This is characterized by a strong reduction in metabolic …
of dormancy known as estivation. This is characterized by a strong reduction in metabolic …
Fetal and neonatal dioxin exposure causes sex-specific metabolic alterations in mice
MP Hoyeck, RC Merhi, C Tulloch… - Toxicological …, 2023 - academic.oup.com
Epidemiological studies report associations between early-life exposure to persistent organic
pollutants (POPs) and impaired metabolic homeostasis in adulthood. We investigated the …
pollutants (POPs) and impaired metabolic homeostasis in adulthood. We investigated the …
[HTML][HTML] The role of MEF2 transcription factors in dehydration and anoxia survival in Rana sylvatica skeletal muscle
MP Hoyeck, H Hadj-Moussa, KB Storey - PeerJ, 2017 - peerj.com
The wood frog (Rana sylvatica) can endure freezing of up to 65% of total body water during
winter. When frozen, wood frogs enter a dormant state characterized by a cessation of vital …
winter. When frozen, wood frogs enter a dormant state characterized by a cessation of vital …
CYP1A1/1A2 enzymes mediate glucose homeostasis and insulin secretion in mice in a sex-specific manner
MEA Ching, MP Hoyeck, L Basu, R Merhi, E van Zyl… - bioRxiv, 2024 - biorxiv.org
Aims/hypothesis: The aryl hydrocarbon receptor (AhR) pathway is involved in cellular
responses to a broad range of external stressors, making it an excellent candidate for …
responses to a broad range of external stressors, making it an excellent candidate for …