User profiles for M. R. Incha
MR InchaPost Doctoral Researcher in the AgileBiofoundry Verified email at lbl.gov Cited by 286 |
Fatty acid and alcohol metabolism in Pseudomonas putida: functional analysis using random barcode transposon sequencing
With its ability to catabolize a wide variety of carbon sources and a growing engineering
toolkit, Pseudomonas putida KT2440 is emerging as an important chassis organism for …
toolkit, Pseudomonas putida KT2440 is emerging as an important chassis organism for …
Anaerobic production of medium-chain fatty alcohols via a β-reduction pathway
In this report, we identify the relevant factors to increase production of medium chain n-alcohols
through an expanded view of the reverse β-oxidation pathway. We began by creating a …
through an expanded view of the reverse β-oxidation pathway. We began by creating a …
[HTML][HTML] Leveraging host metabolism for bisdemethoxycurcumin production in Pseudomonas putida
Pseudomonas putida is a saprophytic bacterium with robust metabolisms and strong solvent
tolerance making it an attractive host for metabolic engineering and bioremediation. Due to …
tolerance making it an attractive host for metabolic engineering and bioremediation. Due to …
Identification, Characterization, and Application of a Highly Sensitive Lactam Biosensor from Pseudomonas putida
Caprolactam is an important polymer precursor to nylon traditionally derived from petroleum
and produced on a scale of 5 million tons per year. Current biological pathways for the …
and produced on a scale of 5 million tons per year. Current biological pathways for the …
Nitrogen metabolism in Pseudomonas putida: functional analysis using random barcode transposon sequencing
Pseudomonas putida KT2440 has long been studied for its diverse and robust metabolisms,
yet many genes and proteins imparting these growth capacities remain uncharacterized. …
yet many genes and proteins imparting these growth capacities remain uncharacterized. …
[HTML][HTML] Engineering Pseudomonas putida KT2440 for chain length tailored free fatty acid and oleochemical production
Despite advances in understanding the metabolism of Pseudomonas putida KT2440, a
promising bacterial host for producing valuable chemicals from plant-derived feedstocks, a strain …
promising bacterial host for producing valuable chemicals from plant-derived feedstocks, a strain …
Growth-coupled bioconversion of levulinic acid to butanone
Common strategies for conversion of lignocellulosic biomass to chemical products center
on deconstructing biomass polymers into fermentable sugars. Here, we demonstrate an …
on deconstructing biomass polymers into fermentable sugars. Here, we demonstrate an …
Robust Characterization of Two Distinct Glutarate Sensing Transcription Factors of Pseudomonas putida l-Lysine Metabolism
A significant bottleneck in synthetic biology involves screening large genetically encoded
libraries for desirable phenotypes such as chemical production. However, transcription factor-…
libraries for desirable phenotypes such as chemical production. However, transcription factor-…
Characterization and diversification of AraC/XylS family regulators guided by transposon sequencing
In this study, we explored the development of engineered inducible systems. Publicly available
data from previous transposon sequencing assays were used to identify regulators of …
data from previous transposon sequencing assays were used to identify regulators of …
[HTML][HTML] Foldy: An open-source web application for interactive protein structure analysis
Foldy is a cloud-based application that allows non-computational biologists to easily utilize
advanced AI-based structural biology tools, including AlphaFold and DiffDock. With many …
advanced AI-based structural biology tools, including AlphaFold and DiffDock. With many …