User profiles for M. T. Doan

Mary T. Doan

University of California Los Angeles
Verified email at mednet.ucla.edu
Cited by 738

[PDF][PDF] A PRDM16-driven metabolic signal from adipocytes regulates precursor cell fate

…, S O'Connor, MT Doan, P Cohen, JA Baur, MT King… - Cell metabolism, 2019 - cell.com
The precursor cells for metabolically beneficial beige adipocytes can alternatively become
fibrogenic and contribute to adipose fibrosis. We found that cold exposure or β3-adrenergic …

Glycerol phosphate shuttle enzyme GPD2 regulates macrophage inflammatory responses

…, M Shibata, HI Aksoylar, J Lei, P Xu, MT Doan… - Nature …, 2019 - nature.com
… Tolerant macrophages mount a blunted response to further LPS challenge and produce
markedly lower amounts of inflammatory cytokines that contribute to the induction of whole-body …

Regulation of nuclear epigenome by mitochondrial DNA heteroplasmy

…, KR Karch, SL Campbell, MT Doan… - Proceedings of the …, 2019 - National Acad Sciences
Diseases associated with mitochondrial DNA (mtDNA) mutations are highly variable in
phenotype, in large part because of differences in the percentage of normal and mutant mtDNAs (…

[PDF][PDF] Quantitative subcellular acyl-CoA analysis reveals distinct nuclear metabolism and isoleucine-dependent histone propionylation

…, K Huber, J Liu, M Noji, S Stransky, J Singh, MT Doan… - Molecular cell, 2022 - cell.com
Quantitative subcellular metabolomic measurements can explain the roles of metabolites in
cellular processes but are subject to multiple confounding factors. We developed stable …

[PDF][PDF] Histone crotonylation promotes mesoendodermal commitment of human embryonic stem cells

Y Fang, X Xu, J Ding, L Yang, MT Doan, PWF Karmaus… - Cell Stem Cell, 2021 - cell.com
Histone crotonylation is a non-acetyl histone lysine modification that is as widespread as
acetylation. However, physiological functions associated with histone crotonylation remain …

Immunotherapy reduces vascular amyloid-β in PDAPP mice

S Schroeter, K Khan, R Barbour, MT Doan… - Journal of …, 2008 - Soc Neuroscience
In addition to parenchymal amyloid-β (Aβ) plaques, Alzheimer's disease (AD) is characterized
by Aβ in the cerebral vasculature [cerebral amyloid angiopathy (CAA)] in the majority of …

O-GlcNAc transferase regulates glioblastoma acetate metabolism via regulation of CDK5-dependent ACSS2 phosphorylation

…, MD Smith, CM Ferrer, S Trefely, LT Izzo, MT Doan… - Oncogene, 2022 - nature.com
Glioblastomas (GBMs) preferentially generate acetyl-CoA from acetate as a fuel source to
promote tumor growth. O-GlcNAcylation has been shown to be elevated by increasing O-…

Coparenting in stepfamilies: Maternal promotion of family cohesiveness with partner and with father

N Favez, ED Widmer, MT Doan, H Tissot - Journal of Child and family …, 2015 - Springer
Coparenting refers to the support parents bring to each other when rearing a child. Supportive
coparenting ensures cohesiveness of the family, which is linked with child outcomes. Little …

[PDF][PDF] Suppression of p16 induces mTORC1-mediated nucleotide metabolic reprogramming

…, M Navaratnarajah, G Zhang, MT Doan… - Cell reports, 2019 - cell.com
Reprogrammed metabolism and cell cycle dysregulation are two cancer hallmarks. p16 is a
cell cycle inhibitor and tumor suppressor that is upregulated during oncogene-induced …

Tri-band bandpass filter using square ring short stub loaded resonators

MT Doan, WQ Che, WJ Feng - Electronics letters, 2012 - IET
A tri-band bandpass filter (BPF) using square ring short stub loaded resonators (SRSLR) is
presented. The characteristics of the triple-mode resonator are investigated by using even/…