User profiles for M. T. Doan
Mary T. DoanUniversity of California Los Angeles Verified email at mednet.ucla.edu Cited by 738 |
[PDF][PDF] A PRDM16-driven metabolic signal from adipocytes regulates precursor cell fate
The precursor cells for metabolically beneficial beige adipocytes can alternatively become
fibrogenic and contribute to adipose fibrosis. We found that cold exposure or β3-adrenergic …
fibrogenic and contribute to adipose fibrosis. We found that cold exposure or β3-adrenergic …
Glycerol phosphate shuttle enzyme GPD2 regulates macrophage inflammatory responses
…, M Shibata, HI Aksoylar, J Lei, P Xu, MT Doan… - Nature …, 2019 - nature.com
… Tolerant macrophages mount a blunted response to further LPS challenge and produce
markedly lower amounts of inflammatory cytokines that contribute to the induction of whole-body …
markedly lower amounts of inflammatory cytokines that contribute to the induction of whole-body …
Regulation of nuclear epigenome by mitochondrial DNA heteroplasmy
…, KR Karch, SL Campbell, MT Doan… - Proceedings of the …, 2019 - National Acad Sciences
Diseases associated with mitochondrial DNA (mtDNA) mutations are highly variable in
phenotype, in large part because of differences in the percentage of normal and mutant mtDNAs (…
phenotype, in large part because of differences in the percentage of normal and mutant mtDNAs (…
[PDF][PDF] Quantitative subcellular acyl-CoA analysis reveals distinct nuclear metabolism and isoleucine-dependent histone propionylation
Quantitative subcellular metabolomic measurements can explain the roles of metabolites in
cellular processes but are subject to multiple confounding factors. We developed stable …
cellular processes but are subject to multiple confounding factors. We developed stable …
[PDF][PDF] Histone crotonylation promotes mesoendodermal commitment of human embryonic stem cells
Histone crotonylation is a non-acetyl histone lysine modification that is as widespread as
acetylation. However, physiological functions associated with histone crotonylation remain …
acetylation. However, physiological functions associated with histone crotonylation remain …
Immunotherapy reduces vascular amyloid-β in PDAPP mice
S Schroeter, K Khan, R Barbour, MT Doan… - Journal of …, 2008 - Soc Neuroscience
In addition to parenchymal amyloid-β (Aβ) plaques, Alzheimer's disease (AD) is characterized
by Aβ in the cerebral vasculature [cerebral amyloid angiopathy (CAA)] in the majority of …
by Aβ in the cerebral vasculature [cerebral amyloid angiopathy (CAA)] in the majority of …
O-GlcNAc transferase regulates glioblastoma acetate metabolism via regulation of CDK5-dependent ACSS2 phosphorylation
Glioblastomas (GBMs) preferentially generate acetyl-CoA from acetate as a fuel source to
promote tumor growth. O-GlcNAcylation has been shown to be elevated by increasing O-…
promote tumor growth. O-GlcNAcylation has been shown to be elevated by increasing O-…
Coparenting in stepfamilies: Maternal promotion of family cohesiveness with partner and with father
Coparenting refers to the support parents bring to each other when rearing a child. Supportive
coparenting ensures cohesiveness of the family, which is linked with child outcomes. Little …
coparenting ensures cohesiveness of the family, which is linked with child outcomes. Little …
[PDF][PDF] Suppression of p16 induces mTORC1-mediated nucleotide metabolic reprogramming
Reprogrammed metabolism and cell cycle dysregulation are two cancer hallmarks. p16 is a
cell cycle inhibitor and tumor suppressor that is upregulated during oncogene-induced …
cell cycle inhibitor and tumor suppressor that is upregulated during oncogene-induced …
Tri-band bandpass filter using square ring short stub loaded resonators
A tri-band bandpass filter (BPF) using square ring short stub loaded resonators (SRSLR) is
presented. The characteristics of the triple-mode resonator are investigated by using even/…
presented. The characteristics of the triple-mode resonator are investigated by using even/…