Zika virus cell tropism in the developing human brain and inhibition by azithromycin
…, C Arias, KA Knopp, MT Laurie… - Proceedings of the …, 2016 - National Acad Sciences
The rapid spread of Zika virus (ZIKV) and its association with abnormal brain development
constitute a global health emergency. Congenital ZIKV infection produces a range of mild to …
constitute a global health emergency. Congenital ZIKV infection produces a range of mild to …
[PDF][PDF] CRISPR interference-based platform for multimodal genetic screens in human iPSC-derived neurons
CRISPR/Cas9-based functional genomics have transformed our ability to elucidate mammalian
cell biology. However, most previous CRISPR-based screens were conducted in cancer …
cell biology. However, most previous CRISPR-based screens were conducted in cancer …
Vaccine breakthrough hypoxemic COVID-19 pneumonia in patients with auto-Abs neutralizing type I IFNs
P Bastard, SE Vazquez, J Liu, MT Laurie… - Science …, 2023 - science.org
Life-threatening “breakthrough” cases of critical COVID-19 are attributed to poor or waning
antibody (Ab) response to SARS-CoV-2 vaccines in individuals already at risk. Preexisting …
antibody (Ab) response to SARS-CoV-2 vaccines in individuals already at risk. Preexisting …
[HTML][HTML] Multiple sclerosis therapies differentially affect SARS-CoV-2 vaccine–induced antibody and T cell immunity and function
…, K Mittl, WM Rowles, K McPolin, JV Rajan, MT Laurie… - JCI insight, 2022 - ncbi.nlm.nih.gov
BACKGROUND Vaccine-elicited adaptive immunity is a prerequisite for control of SARS-CoV-2
infection. Multiple sclerosis (MS) disease-modifying therapies (DMTs) differentially target …
infection. Multiple sclerosis (MS) disease-modifying therapies (DMTs) differentially target …
Performance characteristics of a rapid severe acute respiratory syndrome coronavirus 2 antigen detection assay at a public plaza testing site in San Francisco
We evaluated the performance of the Abbott BinaxNOW rapid antigen test for coronavirus
disease 2019 (Binax-CoV2) to detect virus among persons, regardless of symptoms, at a …
disease 2019 (Binax-CoV2) to detect virus among persons, regardless of symptoms, at a …
[PDF][PDF] Engineered tissue folding by mechanical compaction of the mesenchyme
Many tissues fold into complex shapes during development. Controlling this process in vitro
would represent an important advance for tissue engineering. We use embryonic tissue …
would represent an important advance for tissue engineering. We use embryonic tissue …
[HTML][HTML] Performance characteristics of a rapid SARS-CoV-2 antigen detection assay at a public plaza testing site in San Francisco
We evaluated the performance of the Abbott BinaxNOW™ Covid-19 rapid antigen test to
detect virus among persons, regardless of symptoms, at a public plaza site of ongoing …
detect virus among persons, regardless of symptoms, at a public plaza site of ongoing …
[HTML][HTML] Successful treatment of Balamuthia mandrillaris granulomatous amebic encephalitis with nitroxoline
…, M Shah, A Ramachandran, MT Laurie… - Emerging Infectious …, 2023 - ncbi.nlm.nih.gov
A patient in California, USA, with rare and usually fatal Balamuthia mandrillaris granulomatous
amebic encephalitis survived after receiving treatment with a regimen that included the …
amebic encephalitis survived after receiving treatment with a regimen that included the …
SARS-CoV-2 variant exposures elicit antibody responses with differential cross-neutralization of established and emerging strains including Delta and Omicron
The wide spectrum of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variants with phenotypes impacting transmission and antibody sensitivity necessitates …
variants with phenotypes impacting transmission and antibody sensitivity necessitates …
[HTML][HTML] Systematic functional interrogation of SARS-CoV-2 host factors using Perturb-seq
…, AS Puschnik, JM Replogle, MT Laurie… - Nature …, 2023 - nature.com
Genomic and proteomic screens have identified numerous host factors of SARS-CoV-2, but
efficient delineation of their molecular roles during infection remains a challenge. Here we …
efficient delineation of their molecular roles during infection remains a challenge. Here we …