The action potential

MW Barnett, PM Larkman - Practical neurology, 2007 - pn.bmj.com
… Mark W Barnett1, … Correspondence to: Dr MW Barnett Centre for Integrative Physiology,
School of Biomedical Sciences, University of Edinburgh, Edinburgh EH8 9XD, UK; M.…

Somatic retrotransposition alters the genetic landscape of the human brain

JK Baillie, MW Barnett, KR Upton, DJ Gerhardt… - Nature, 2011 - nature.com
Retrotransposons are mobile genetic elements that use a germline ‘copy-and-paste’ mechanism
to spread throughout metazoan genomes 1 . At least 50 per cent of the human genome …

[HTML][HTML] A gene expression atlas of the domestic pig

TC Freeman, A Ivens, JK Baillie, D Beraldi, MW Barnett… - BMC biology, 2012 - Springer
Background This work describes the first genome-wide analysis of the transcriptional landscape
of the pig. A new porcine Affymetrix expression array was designed in order to provide …

Erk MAP kinase regulates branching morphogenesis in the developing mouse kidney

CE Fisher, L Michael, MW Barnett, JA Davies - 2001 - journals.biologists.com
Branching morphogenesis of epithelium is a common and important feature of organogenesis;
it is, for example, responsible for development of renal collecting ducts, lung airways, milk …

Signalling by glial cell line-derived neurotrophic factor (GDNF) requires heparan sulphate glycosaminoglycan

MW Barnett, CE Fisher, G Perona-Wright… - Journal of cell …, 2002 - journals.biologists.com
Glial cell line-derived neurotrophic factor, GDNF, is vital to the development and maintenance
of neural tissues; it promotes survival of sympathetic, parasympathetic and spinal motor …

[HTML][HTML] SynGAP isoforms exert opposing effects on synaptic strength

AC McMahon, MW Barnett, TS O'leary… - Nature …, 2012 - nature.com
Alternative promoter usage and alternative splicing enable diversification of the transcriptome.
Here we demonstrate that the function of Synaptic GTPase-Activating Protein (SynGAP), a …

Assembly of a parts list of the human mitotic cell cycle machinery

B Giotti, SH Chen, MW Barnett, T Regan… - Journal of molecular …, 2019 - academic.oup.com
The set of proteins required for mitotic division remains poorly characterized. Here, an
extensive series of correlation analyses of human and mouse transcriptomics data were …

[HTML][HTML] Characterisation of the British honey bee metagenome

T Regan, MW Barnett, DR Laetsch, SJ Bush… - Nature …, 2018 - nature.com
The European honey bee (Apis mellifera) plays a major role in pollination and food production.
Honey bee health is a complex product of the environment, host genetics and associated …

[HTML][HTML] The transcriptional signature associated with human motile cilia

A Patir, AM Fraser, MW Barnett, L McTeir, J Rainger… - Scientific reports, 2020 - nature.com
Cilia are complex microtubule-based organelles essential to a range of processes associated
with embryogenesis and tissue homeostasis. Mutations in components of these organelles …

Analysis of the transcriptional networks underpinning the activation of murine macrophages by inflammatory mediators

S Raza, MW Barnett, Z Barnett-Itzhaki… - Journal of leukocyte …, 2014 - academic.oup.com
Macrophages respond to the TLR4 agonist LPS with a sequential transcriptional cascade
controlled by a complex regulatory network of signaling pathways and transcription factors. At …