User profiles for M. Achtman

Mark Achtman FRS

emeritus Professor University of Warwick, previously University College Cork and Max …
Verified email at warwick.ac.uk
Cited by 42574

[HTML][HTML] Microbial diversity and the genetic nature of microbial species

M Achtman, M Wagner - Nature reviews microbiology, 2008 - nature.com
The earth contains a huge number of largely uncharacterized Bacteria and Archaea.
Microbiologists are struggling to summarize their genetic diversity and classify them, which has …

[HTML][HTML] A genomic overview of the population structure of Salmonella

NF Alikhan, Z Zhou, MJ Sergeant, M Achtman - PLoS genetics, 2018 - journals.plos.org
… Due to the polyphyletic nature of serovars and an error rate of serotyping of at least several
percent, Achtman et al. also recommended ‘phasing out the routine use of serovars, and …

Evolution, population structure, and phylogeography of genetically monomorphic bacterial pathogens

M Achtman - Annu. Rev. Microbiol., 2008 - annualreviews.org
… was within the M. tuberculosis complex, in which sequencing 31 kb of coding sequences
from multiple strains revealed 30 synonymous SNPs (sSNPs) (76). M. tuberculosis probably …

Multilocus sequence typing: a portable approach to the identification of clones within populations of pathogenic microorganisms

…, DA Caugant, IM Feavers, M Achtman… - Proceedings of the …, 1998 - National Acad Sciences
Traditional and molecular typing schemes for the characterization of pathogenic microorganisms
are poorly portable because they index variation that is difficult to compare among …

Sex and virulence in Escherichia coli: an evolutionary perspective

…, MCJ Maiden, H Ochman, M Achtman - Molecular …, 2006 - Wiley Online Library
Pathogenic Escherichia coli cause over 160 million cases of dysentery and one million deaths
per year, whereas non‐pathogenic E. coli constitute part of the normal intestinal flora of …

Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica

…, L Temple, K James, B Harris, MA Quail, M Achtman… - Nature …, 2003 - nature.com
Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica are closely
related Gram-negative β-proteobacteria that colonize the respiratory tracts of mammals. B. …

Traces of Human Migrations in Helicobacter pylori Populations

…, U Reichard, E Katzowitsch, X Wang, M Achtman… - science, 2003 - science.org
Helicobacter pylori, a chronic gastric pathogen of human beings, can be divided into seven
populations and subpopulations with distinct geographical distributions. These modern …

Complete DNA sequence of a serogroup A strain of Neisseria meningitidis Z2491

J Parkhill, M Achtman, KD James, SD Bentley… - Nature, 2000 - nature.com
Neisseria meningitidis causes bacterial meningitis and is therefore responsible for considerable
morbidity and mortality in both the developed and the developing world. Meningococci …

Yersinia pestis, the cause of plague, is a recently emerged clone of Yersinia pseudotuberculosis

M Achtman, K Zurth, G Morelli… - Proceedings of the …, 1999 - National Acad Sciences
Plague, one of the most devastating diseases of human history, is caused by Yersinia pestis.
In this study, we analyzed the population genetic structure of Y. pestis and the two other …

An African origin for the intimate association between humans and Helicobacter pylori

…, T Wadstrom, S Suerbaum, M Achtman - Nature, 2007 - nature.com
Infection of the stomach by Helicobacter pylori is ubiquitous among humans. However,
although H. pylori strains from different geographic areas are associated with clear …