Automated molecular docking aims at predicting the possible interactions between two
molecules. This method has proven useful in medicinal chemistry and drug discovery providing …

El comportamiento térmico del almidón de maíz (Sigma Aldrich) se estudió a través de
calorimetría diferencial de barrido (DSC). El pico endotérmico observado en el perfil DSC se …

El acoplamiento molecular automatizado tiene como objetivo proponer un modelo de unión
entre dos moléculas. Este método ha sido útil en química farmacéutica y en el …

… This finding is in line with our extrapolation of the T m to weak K i -values that also suggests
a lower structural stability of an inhibitor-free on state of furin. The MD simulations indicate …

Reactivation of p53 by release of the functional protein from its inhibition by MDM2 provides
an efficient, nongenotoxic approach to a wide variety of cancers. We present the cocrystal …

… In a further method development, we treated C222 1 crystals with 1 M TMAO as a cryoprotectant
and lattice stabilizer (35) using a free mounting system soaking-based method (36). We …

… an IC 50 of 230 μM (K i =23 μM; Table 1) with no inhibition observed for the C- and T-like
activities even at an inhibitor concentration of 200 μM (Figure S2 in the Supporting Information). …

Una literatura creciente en neuropsicología estudia el juicio moral aplicando dilemas
morales a personas con daños neuronales o con rasgos de personalidad antisocial; y parece …

The Transient Receptor Potential Vanilloid 4 (TRPV4) channel has been shown to function
in many physiological and pathophysiological processes. Despite abundant information on …

El libro Karl Kohn relata la biografía de este prestigioso arquitecto, diseñador y artista checo
que emigró al Ecuador en 1939. Desde su llegada se integró a la vida cultural del país y de …